Schizophrenia US Medical PG Flashcards - Medical Study Cards
Master Schizophrenia with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Schizophrenia Flashcard Deck - 41 Cards
Flashcard 1: schizophrenia
Answer:
Extra: increased: dopamine
Flashcard 2: Are typical antipsychotics effective at treating the positive or negative symptoms of schizophrenia?
_____
Answer: Positive
Extra:
Sketchy Pharmacology: Neuro/Psych
Watch First generation antipsychotics [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-neuro-psych/videos/medical-pharmacology-neuropsych-antipsychotics-and-parkinsons-first-generation-antipsychotics?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/psychiatry/videos/pharmacology?index=14]
https://onlinemeded.org/spa/psychiatry?ref=anki
Flashcard 3: Schizophrenia is associated with _____-creased serotonergic activity and decreased dendritic branching
Answer: in
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/psychiatry/videos/psychotic-and-mood-disorders?index=10]
https://onlinemeded.org/spa/psychiatry?ref=anki
Flashcard 4: Is the prevalence of schizophrenia more common in a particular race?
_____
Answer: No
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/psychiatry/videos/psychotic-and-mood-disorders?index=10]
https://onlinemeded.org/spa/psychiatry/psychotic-disorders/acquire?ref=anki
Flashcard 5: Which type of aphasia is characterized by the following:
_____
1. Fluent speech
2. Impaired comprehension
3. Impaired repetition
Answer: Wernicke (receptive) aphasia
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/neurology/videos/cerebral-cortext?index=4]
https://onlinemeded.org/spa/neurology?ref=anki
Flashcard 6: Which atypical antipsychotic is used for suicidality in schizophrenia?
_____
Answer: Clozapine
Extra:
First Aid Pharmacology: Neuro/Psych
Watch Second generation antipsychotics [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-neuro-psych/videos/medical-pharmacology-neuropsych-antipsychotics-and-parkinsons-second-generation-antipsychotics?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/psychiatry/videos/psychotic-and-mood-disorders?index=10]
https://onlinemeded.org/spa/psychiatry?ref=anki
Imagine a schizophrenic dude in the closet (lock inside to prevent suicide - reduces suicide risk)
Flashcard 7: Diagnosis of schizophrenia requires at least 2 of following, and at least 1 of these should include 1 to 3:
- Positive symptoms-
1. Delusions
2. Hallucinations
3. Disorganized speech
4. Disorganized or catatonic behavior
5. _____ symptoms (affective flattening, avolition, anhedonia, asociality, alogia)
Answer: Negative
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/psychiatry/videos/psychotic-and-mood-disorders?index=10]
https://onlinemeded.org/spa/psychiatry/psychotic-disorders/acquire?ref=anki
Flashcard 8: Schizophrenia is associated with _____ dendritic branching
Answer: decreased
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/psychiatry/videos/psychotic-and-mood-disorders?index=10]
https://onlinemeded.org/spa/psychiatry/psychotic-disorders/acquire?ref=anki
Flashcard 9: Schizophrenia is characterized by _____ on CT
Answer: ventriculomegaly
Extra:
https://onlinemeded.org/spa/psychiatry/psychotic-disorders/acquire?ref=anki
Flashcard 10: _____ = only appropriate after failing 2 other drugs (refractory schizophrenia)
Answer: Clozapine
Extra:
https://onlinemeded.org/spa/psychiatry?ref=anki
Flashcard 11: _____ = ↓ suicide risk in schizophrenia
Answer: Clozapine
Extra:
https://onlinemeded.org?ref=anki
Flashcard 12: What dopaminergic pathway abnormalities are theorized to be responsible for the positive and negative symptoms of schizophrenia?
Positive symptoms: _____
Negative symptoms: _____
Answer: excessive mesolimbic dopaminergic activity
Extra:
https://onlinemeded.org/spa/psychiatry?ref=anki
Flashcard 13: Acute and late onset schizophrenia = _____ prognosis
Answer: good
Extra:
https://onlinemeded.org?ref=anki
Flashcard 14: What is the dopamine hypothesis of the etiology of schizophrenia?
_____
Answer: Increased DA activity and receptors in some brain regions yield positive symptoms
Decreased DA activity and receptors in other regions yield negative symptoms
Extra:
https://onlinemeded.org/spa/psychiatry/psychotic-disorders/acquire?ref=anki
Flashcard 15: The DSM-5 criteria for schizophrenia include:
A. At least two of the following symptoms (at least one must be 1, 2, or 3), each present for a significant portion of time during a one-month period:
1. _____
2. _____
3. _____
4. Disorganized or catatonic behavior
5. Negative symptoms
B. Significant impairment in social or occupational functioning
C. Continuous signs of the disturbance persist for ≥ 6 months
*May include periods of prodromal or residual symptoms
D./E. Not better explained by another mental disorder, medical condition, or substance
F. If there is a history of autism spectrum disorder, diagnosis of schizophrenia is made only if prominent delusions or hallucinations
Answer: Delusions
Extra:
https://onlinemeded.org/spa/psychiatry?ref=anki
Flashcard 16: Favorable prognostic factors in schizophrenia include acute onset, identifiable precipitant, older age at onset, and predominantly _____ psychotic symptoms
Answer: positive
Extra:
https://onlinemeded.org?ref=anki
Flashcard 17: Lifetime prevalence of schizophrenia ≈ _____
Answer: 1%
Extra:
https://onlinemeded.org?ref=anki
Flashcard 18: Blockage of the mesocortical dopamine pathway results in increased _____" symptoms of schizophrenia.
Answer: negative
Extra:
https://onlinemeded.org?ref=anki
Flashcard 19: First generation (typical) antipsychotics treat _____ symptoms of schizophrenia
Second generation (atypical) antipsychotics treat _____ symptoms of schizophrenia
Answer: (+)
Extra:
https://onlinemeded.org/spa/psychiatry/psychotic-disorders/acquire?ref=anki
Flashcard 20: _____ = ↓ suicide risk in schizophrenia
Answer: Clozapine
Extra:
First Aid Pharmacology: Neuro/Psych
https://onlinemeded.org?ref=anki
Flashcard 21: What class of antipsychotics is considered first-line therapy in newly diagnosed schizophrenia?
_____
Answer: Atypical
Extra:
https://onlinemeded.org/spa/psychiatry?ref=anki
Flashcard 22: Which dopaminergic pathway is associated with the positive symptoms of schizophrenia?
_____
Answer: Mesolimbic
Extra:
https://onlinemeded.org/spa/psychiatry?ref=anki
Flashcard 23: Flat or blunted affect, anhedonia, apathy, alogia, and lack of interest in socialization describe what category of symptoms of schizophrenia?
_____
Answer: Negative symptoms
Extra:
https://onlinemeded.org/spa/psychiatry/psychotic-disorders/acquire?ref=anki
Flashcard 24: Schizophrenia is associated with _____-creased serotonergic activity and decreased dendritic branching.
Answer: in
Flashcard 25: Schizophrenia is a chronic mental disorder with periods of psychosis, disturbed behavior and thought, and decline in functioning lasting _____ (duration)
Answer: > 6 months
Flashcard 26: What neurotransmitter is increased in schizophrenia? _____
Answer: Dopamine
Flashcard 27: Are patients with schizoid personality disorder content with social isolation? _____
Answer: Yes
Flashcard 28: Schizophrenia is associated with _____ dendritic branching
Answer: decreased
Flashcard 29: Are typical antipsychotics effective at treating the positive or negative symptoms of schizophrenia? _____
Answer: Positive
Flashcard 30: Which dopaminergic pathway is the primary target for the antipsychotic treatment of schizoprenia? _____
Answer: Mesolimbic pathway
Flashcard 31: Schizophrenia is associated with _____ dopaminergic activity
Answer: increased
Flashcard 32: Is the prevalence of schizophrenia more common in a particular race?_____
Answer: No
Flashcard 33: Are atypical antipsychotics effective at treating the positive or negative symptoms of schizophrenia? _____
Answer: Both
Flashcard 34: Are 1st-generation anti-psychotic drugs effective at reducing the "negative symptoms" associated with schizophrenia? _____
Answer: No (limited effect)
Flashcard 35: Schizophrenia/psychosis in teens is associated with frequent _____ use
Answer: cannabis
Flashcard 36: Which atypical antipsychotic is used for suicidality in schizophrenia? _____
Answer: Clozapine
Flashcard 37: Which atypical antipsychotic is used for treatment-resistant schizophrenia or schizoaffective disorder? _____
Answer: Clozapine
Flashcard 38: Schizophrenia is characterized by _____ on CT
Answer: ventriculomegaly
Flashcard 39: What group of drugs is the first line treatment for schizophrenia? _____
Answer: Atypical antipsychotics (e.g. risperidone)
Flashcard 40: Are anti-psychotic drugs effective at reducing the "positive symptoms" associated with schizophrenia? _____
Answer: Yes
Flashcard 41: Is schizophrenia more common in men or women?_____
Answer: Men
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