Fever pathophysiology — Flashcards

Flashcard 1: The _____ hypothalamus senses decreased body temperatures and mediates responses to conserve heat

Answer: posterior

Flashcard 2: Which female sex steroid is responsible for increased body temperature?_____

Answer: Progesterone

Flashcard 3: Exposure to cold temperatures causes _____ sympathetic nervous system activity

Answer: increased

Flashcard 4: Which form(s) of cyclooxygenase synthesize prostaglandins that dilate the afferent arteriole? _____

Answer: Both COX-1 and COX-2

Flashcard 5: Mechanisms for dissipating heat are coordinated in the _____ hypothalamus

Answer: anterior

Flashcard 6: Patients develop heat stroke due to heat production exceeding _____

Answer: heat dissipation

Flashcard 7: Hypothalamic center responsible for thermoregulation against HEATING:

Answer: Anterior hypothalamus (Preoptic area) :: center for cooling?

Extra: The anterior hypothalamus/preoptic area (AH/POA) handles heat dissipation (cooling), while the posterior hypothalamus handles heat conservation (heating). Remember: A/C = Anterior Cooling.

Flashcard 8: Hypothalamic center for heat dissipation (cooling)

Answer: Anterior hypothalamus (Preoptic area)

Extra: Mnemonic: Anterior = Cooling (A/C) Posterior = Heating (P/H)

Flashcard 9: What is the effect of the cytokines released by activated macrophages?

Answer: fever, hypotension