RAAS — Flashcards

Flashcard 71: What clinical features are seen in 17α-hydroxylase deficiency that are a result of decreased androgen levels in females? _____

Answer: Lack of sexual development; e.g. lack pubic and axillary hair

Flashcard 72: ACE is primarily located in the vascular endothelium of the _____

Answer: lungs

Extra: FA2020 UPDATE: ACE inhibitors dilate the efferent arteriole, not constrict as the image below states: Sketchy Pharmacology: Cardiovascular/Renal

Flashcard 73: Decreases in ECF volume (e.g. hemorrhage or decreased Na+) cause a decrease in renal perfusion pressure, which in turn increases secretion of the enzyme _____

Answer: renin

Flashcard 74: Growth hormone inhibits its own secretion by stimulating the secretion of _____ from the hypothalamus

Answer: somatostatin

Flashcard 75: Dysfunction of the hypothalamus gland leads to _____ prolactin levels

Answer: increased

Flashcard 76: Ovarian granulosa cells may produce _____, which stimulates FSH secretion from the anterior pituitary

Answer: activin

Flashcard 77: The major mineralocorticoid produced in humans is _____

Answer: aldosterone

Flashcard 78: Which arterioles of the kidney (afferent or efferent) are more sensitive to angiotensin II? _____

Answer: Efferent arterioles

Flashcard 79: 1° hyperaldosteronism does not directly cause edema or hypernatremia due to _____ and pressure naturesis mechanisms

Answer: aldosterone escape

Flashcard 80: _____ is a hormone that increases renal Na+ reabsorption, thereby restoring ECF volume and blood volume to normal

Answer: Aldosterone