RAAS — Flashcards

Flashcard 101: Angiotensin II stimulates _____ exchange in the proximal tubule

Answer: Na+-H+

Flashcard 102: The renin-angiotensin II-aldosterone system is activated in response to a _____ in mean arterial pressure

Answer: decrease

Flashcard 103: Destruction of the hypothalamus or interruption of the hypothalamic-hypophysial tract result in prolactin excess by causing loss of _____

Answer: tonic inhibition by dopamine

Flashcard 104: How does cortisol affect secretion of CRH from the hypothalamus?_____

Answer: inhibits secretion, both directly and indirectly

Flashcard 105: Which hormones (2) are released in response to increased volume, and thus act as a "check" on the renin-angiotensin-aldosterone system? _____

Answer: ANP, BNP

Flashcard 106: What is the effect of insulin on glucagon secretion?_____

Answer: Decreased

Extra: Within the pancreatic islets, insulin (from $\beta$ cells) inhibits glucagon secretion (from $\alpha$ cells) via paracrine signaling. Other paracrine relationships in the pancreas: * **Glucagon** stimulates insulin and somatostatin secretion. * **Somatostatin** inhibits both insulin and glucagon secretion.

Flashcard 107: How does growth hormone affect its own secretion from the anterior pituitary?_____

Answer: Decreased, indirectly

Flashcard 108: Which cholecystokinin receptor is equally sensitive to gastrin and CCK? _____

Answer: CCKB

Flashcard 109: Aldosterone leads to _____ epithelial Na+ channel (ENaC) activity

Answer: increased

Flashcard 110: What is the effect of increased temperature on inhibin B secretion? _____

Answer: decreased