Microcirculation physiology — Flashcards

Flashcard 1: In the Starling equation for capillary fluid exchange, what does πc represent?

Answer: Capillary oncotic pressure (colloid osmotic pressure)

Flashcard 2: The Starling equation for fluid flow (Jv) is:

Answer: Kf [(Pc - Pi) - σ(πc - πi)]

Extra: Kf = Filtration coefficient (capillary permeability) Pc = Capillary hydrostatic pressure Pi = Interstitial hydrostatic pressure σ = Reflection coefficient (permeability to protein) πc = Capillary oncotic pressure πi = Interstitial oncotic pressure

Flashcard 3: What is the major factor determining autoregulation of blood flow to the exercising skeletal muscle?

Answer: Local metabolites

Flashcard 4: Blood flow (Q) is _____ proportional to the resistance of blood vessels

Answer: inversely

Flashcard 5: Edema may be caused by _____ plasma proteins (c)

Answer: decreased

Flashcard 6: Kwashiorkor may present with edema (due to decreased plasma _____ pressure) and skin lesions

Answer: oncotic

Flashcard 7: What does σ (sigma) represent in regards to capillary fluid exchange?

Answer: Reflection coefficient

Extra: The reflection coefficient (σ) is a value between 0 and 1 that describes the permeability of a membrane to a solute (usually plasma proteins). • σ = 1: The membrane is impermeable (100% reflection). • σ = 0: The membrane is completely permeable.

Flashcard 8: What type of resistance is illustrated by the arrangement of blood vessels in systemic circulation? _____

Answer: Parallel resistance

Flashcard 9: The rate at which blood is pumped from either ventricle is called the _____

Answer: cardiac output

Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/cardiology/videos/cardiac-parameters-of-physiologic-function?index=10] https://onlinemeded.org/spa/cardiac/anatomy-of-the-heart/acquire?ref=anki 

Flashcard 10: Both ADH and oxytocin are neuropeptides, synthesized in hypothalamic neurons and secreted from nerve terminals in the _____

Answer: posterior pituitary

Extra:   Watch Hypothalamic & Pituitary Dysfunction Etiologies [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-endocrine/videos/medical-pathophysiology-endocrine-hypothalamic-and-pituitary-disorders-hypothalamic-and-pituitary-dysfunction-etiologies?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/histology/videos/endocrine-system?index=23] https://onlinemeded.org/spa/endocrinology?ref=anki