GI motility patterns and regulation — Flashcards

Flashcard 1: Intestinal peristalsis occurs in response to binding of _____ to intrinsic primary afferent neurons (IPANs)

Answer: 5-HT (serotonin)

Flashcard 2: Motilin is secreted from the small intestine during _____ states (fed or fasting)

Answer: fasting

Flashcard 3: Slow waves originate in the _____, which serve as the pacemaker for GI smooth muscle

Answer: interstitial cells of Cajal

Flashcard 4: _____ are oscillating membrane potentials inherent to the smooth muscle cells of some parts of the GI tract

Answer: Slow waves

Flashcard 5: The _____ nervous system is usually inhibitory on functions of the GI tract

Answer: sympathetic

Flashcard 6: _____ contractions are designed to propel the chyme along the small intestine towards the large intestine

Answer: Peristaltic

Flashcard 7: The _____ nervous system is usually excitatory on functions of the GI tract

Answer: parasympathetic

Flashcard 8: satiety

Answer: ventromedial area of the hypothalamus

Flashcard 9: What is the function of the area postrema?

Answer: Chemoreceptor trigger zone (CTZ) / Vomiting center

Extra: The area postrema is a circumventricular organ located in the medulla (floor of the 4th ventricle) that lacks a blood-brain barrier, allowing it to detect emetic toxins in the blood.

Flashcard 10: Give two cell types rich in rough endoplasmic reticulum (RER).

Answer: intestinal goblet cells, plasma cells