Antifungals — Flashcards

Toxicity of _____ (drug) results from non-selective binding on mammalian cholesterol membranes

Terbinafine is used to treat superficial _____ infections

Which class of antifungals can result in histamine-mediated hypersensitivity reactions?_____

Which of the allylamines is associated with GI upset?_____

Which antifungal prevents candidiasis in patients undergoing hematopoietic stem cell transplant?_____

Which renal tubular acidosis may be caused by amphoterecin B toxicity?_____

Is sirolimus (rapamycin) nephrotoxic?_____

Should azoles (ie: ketoconazole) be avoided during pregnancy?_____

For more severe Tinea infections or persistent Onychomycosis (manifestations of dermatophytes), oral _____ is used

Which class of antifungals treat invasive aspergillosis that is refractory to voriconazole?_____