Immunotherapies and checkpoint inhibitors US Medical PG Flashcards - Medical Study Cards
Master Immunotherapies and checkpoint inhibitors with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Immunotherapies and checkpoint inhibitors Flashcard Deck - 10 Cards
Flashcard 1: Ipilimumab is a checkpoint inhibitor that binds to _____ on T cells.
Answer: CTLA-4
Flashcard 2: Carfilzomib and Bortezomib are examples of antineoplastics that work by inhibiting the _____
Answer: proteasome
Flashcard 3: Erlotinib therapy is associated with _____ and diarrhea (adverse effects)
Answer: acneiform skin rash
Flashcard 4: Because Pembrolizumab targets a peripheral tolerance mechanism, patients taking this drug can develop autoimmune disorders of _____ organs
Answer: endocrine
Flashcard 5: Nivolumab is an anti-checkpoint monoclonal antibody that binds to _____ on T cells.
Answer: PD-1
Flashcard 6: anastrazole
Answer:
Extra: breast cancer in postmenopausal women aromatase inhibitor
Flashcard 7: exemestane
Answer:
Extra: breast cancer in postmenopausal women aromatase inhibitor
Flashcard 8: alkylating agents
Answer: absence of digits (and multiple varied anomalies)
Flashcard 9: folate antagonists
Answer: neural tube defects
Flashcard 10: methotrexate (MTX)
Answer:
Extra: inhibits eukaryotic dihydrofolate reductase
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