Alkylating agents US Medical PG Flashcards - Medical Study Cards
Master Alkylating agents with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Alkylating agents Flashcard Deck - 10 Cards
Flashcard 1: What is the mechanism of resistance to Acyclovir/Famciclovir/Valacyclovir?_____
Answer: Mutated/Absent Thymidine Kinase
Flashcard 2: Which two alkylating agents must be activated by CYP450 in the liver?_____
Answer: Cyclophosphamide, Ifosfamide
Flashcard 3: Which alkylating agent is used to treat both hematologic malignancies (leukemia, lymphoma) and solid tumors?_____
Answer: Cyclophosphamide
Flashcard 4: What class of drugs does cyclophosphamide belong to?_____
Answer: Alkylating agents (cytotoxic chemo)
Flashcard 5: What is the mechanism of Chloramphenicol resistance?_____
Answer: Plasmid-encoded acetyltransferases that inactivate the drug
Flashcard 6: anastrazole
Answer:
Extra: breast cancer in postmenopausal women aromatase inhibitor
Flashcard 7: exemestane
Answer:
Extra: breast cancer in postmenopausal women aromatase inhibitor
Flashcard 8: alkylating agents
Answer: absence of digits (and multiple varied anomalies)
Flashcard 9: folate antagonists
Answer: neural tube defects
Flashcard 10: methotrexate (MTX)
Answer:
Extra: inhibits eukaryotic dihydrofolate reductase
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