Group B streptococcal disease — Flashcards

Flashcard 1: What is the first type of immunoglobulin produced in a neonate? _____

Answer: IgM

Flashcard 2: What is the drug of choice for the treatment of neonatal conjunctivitis caused by **Chlamydia trachomatis**?

Answer: Oral Erythromycin

Extra: Treatment for neonatal conjunctivitis (Ophthalmia neonatorum): - **Chlamydia trachomatis** (5–14 days): Oral Erythromycin. Monitor for infantile hypertrophic pyloric stenosis (IHPS). - **Neisseria gonorrhoeae** (2–5 days): Single dose of IM or IV Ceftriaxone. - **Prophylaxis**: Topical Erythromycin 0.5% ointment is given at birth (prevents Gonorrhea, less effective for Chlamydia).

Flashcard 3: What GI pathology is associated with the hypoxemia seen in neonatal respiratory distress syndrome?

Answer: Necrotizing enterocolitis

Flashcard 4: What is the most common cause of meningitis in neonates?_____

Answer: Group B Strep (Streptococcus agalactiae)

Flashcard 5: Rash that occurs in neonates; will have + Nikolsky sign: _____

Answer: Scalded-Skin Syndrome

Flashcard 6: Congenital toxoplasmosis classically presents with the triad of chorioretinitis, hydrocephalus, and _____.

Answer: diffuse intracranial calcifications

Extra: Congenital Toxoplasmosis Classic Triad: 1. Chorioretinitis 2. Hydrocephalus 3. Diffuse intracranial calcifications Note: Ring-enhancing lesions on CT/MRI are characteristic of Toxoplasmosis in HIV/immunocompromised patients, not typically the congenital form. Watch Toxoplasma gondii: https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-parasites/videos/medical-microbiology-parasites-protozoa-of-the-cns-toxoplasma-gondii

Flashcard 7: Congenital toxoplasmosis presents with _____, which may manifest with macrocephaly and seizures.

Answer: hydrocephalus

Extra: Congenital Toxoplasmosis classic triad: 1. Chorioretinitis 2. Hydrocephalus (obstructive) 3. Diffuse intracranial calcifications Hydrocephalus in toxoplasmosis is often caused by aqueductal stenosis resulting from inflammation and scarring. Seizures and macrocephaly are common clinical manifestations of the hydrocephalus and brain involvement.

Flashcard 8: Erythromycin eye ointment is indicated as prophylaxis for _____ conjunctivitis in the newborn

Answer: gonococcal

Extra:    https://onlinemeded.org/spa/infectious-disease?ref=anki 

Flashcard 9: _____ is the deposition of bilirubin in the brain, especially basal ganglia, causing neurologic deficits and possibly death

Answer: Kernicterus

Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/pancreatic-and-biliary-pathology?index=16] https://onlinemeded.org/spa/gastroenterology/jaundice/acquire?ref=anki Atlas: 

Flashcard 10: Streptococcus agalactiae (GBS) causes neonatal meningitis, _____, and pneumonia

Answer: sepsis

Extra:   https://onlinemeded.org/spa/infectious-disease/pneumonia/acquire?ref=anki