Endocrine pathology — Flashcards

Flashcard 1: Which Langerhans cell histiocytosis presents as scalp rash, lytic skull lesions, diabetes insipidus, and exophthalmos?_____

Answer: Hand-Schuller-Christian disease

Flashcard 2: What two underlying pathologies are associated with hyaline arteriolosclerosis? _____

Answer: Benign hypertension, diabetes

Flashcard 3: Patients with Hashimoto thyroiditis have an increased risk for _____; presents as an enlarging thyroid late in disease course

Answer: B-cell (marginal zone) lymphoma

Flashcard 4: Ammonium magnesium phosphate (struvite) kidney stones classically form _____ in renal calyces

Answer: staghorn calculi

Flashcard 5: Riedel thyroiditis is characterized by replacement of thyroid by _____ tissue with inflammatory infiltrate

Answer: fibrous

Flashcard 6: What MSK pathology is characterized by thick, heavy bone that fractures easily due to imbalance of osteoblast and osteoclast function? _____

Answer: Paget disease of bone (osteitis deformans)

Flashcard 7: _____ is the age-related hyperplasia of prostatic stroma and glands

Answer: Benign prostatic hyperplasia (BPH)

Flashcard 8: Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) has the potential to present with cysts in the _____

Answer: medullary collecting ducts

Flashcard 9: A necrotizing skin condition of diabetes mellitus that occurs more commonly in women is _____

Answer: necrobiosis lipoidica diabeticorum

Flashcard 10: Niemann-Pick disease

Answer:

Extra: accumulation of sphingomyelinprogressive neurodegeneration, hepatosplenomegaly, cherry-red spot on macula foam cells Ashkenazi JewAR sphingomyelinase