Primary CNS tumors — Flashcards

Flashcard 1: The tumor cells of pilocytic astrocytomas stain positive for _____

Answer: GFAP

Flashcard 2: The tumor cells of a Schwannoma stain positive for _____

Answer: S-100

Flashcard 3: The tumor cells of glioblastoma multiforme stain positive for _____

Answer: GFAP

Flashcard 4: Medulloblastoma is a form of primitive _____ tumor (embryonic tissue origin)

Answer: neuroectodermal

Flashcard 5: Meningiomas are characterized histologically by presence of _____ bodies

Answer: psammoma

Flashcard 6: What is the associated tumor that results from overexpression of the PDGFB oncogene?_____

Answer: Astrocytoma

Flashcard 7: The CNS tumor that is histologically identical to testicular seminoma and ovarian dysgerminoma is the _____.

Answer: Germinoma

Extra: Germinomas are the most common tumors of the pineal gland and are histologically identical to testicular seminoma and ovarian dysgerminoma. They characteristically present with Parinaud syndrome (vertical gaze palsy) due to compression of the tectal plate.

Flashcard 8: What is the prognosis of medulloblastoma? _____

Answer: Highly malignant (WHO Grade IV), but radiosensitive

Flashcard 9: Oligodendroglioma is a _____ tumor of oligodendrocytes

Answer: malignant

Flashcard 10: What is the term for infarcted tissue in the basal ganglia or internal capsule caused by occlusion of a lenticulostriate artery?

Answer: lacunar infarct