Amyotrophic lateral sclerosis — Flashcards

10 flashcards

Niemann Pick disease may present with progressive _____

Which disease is characterized by degeneration of both the lateral corticospinal tracts and the anterior horn cells in the spinal cord?

As limb compartment syndrome progresses, patients can develop _____ deficits

Tabes Dorsalis is characterized by _____ joints due to loss of proprioception

Spongiform encephalopathy is characterized histologically by intracellular _____ due to damage to neurons and glial cells

Frontotemporal dementia may have ubiquitinated _____ inclusions seen on histology

Werdnig-Hoffmann disease is the infantile form (type 1) of _____

What lysosomal storage disease presents with central and peripheral demyelination with ataxia and dementia?_____

What is the term for infarcted tissue in the basal ganglia or internal capsule caused by occlusion of a lenticulostriate artery?

#10

epidural hematoma

Amyotrophic lateral sclerosis US Medical PG Flashcards - Medical Study Cards

Master Amyotrophic lateral sclerosis with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.

Amyotrophic lateral sclerosis Flashcard Deck - 10 Cards

Flashcard 1: Niemann Pick disease may present with progressive _____

Answer: neurodegeneration

Flashcard 2: Which disease is characterized by degeneration of both the lateral corticospinal tracts and the anterior horn cells in the spinal cord?

Answer: Amyotrophic lateral sclerosis (ALS)

Flashcard 3: As limb compartment syndrome progresses, patients can develop _____ deficits

Answer: motor

Flashcard 4: Tabes Dorsalis is characterized by _____ joints due to loss of proprioception

Answer: charcot

Flashcard 5: Spongiform encephalopathy is characterized histologically by intracellular _____ due to damage to neurons and glial cells

Answer: vacuoles

Flashcard 6: Frontotemporal dementia may have ubiquitinated _____ inclusions seen on histology

Answer: TDP-43

Extra: Frontotemporal Lobar Degeneration (FTLD) is divided into subtypes based on the protein inclusions: 1. **FTLD-TDP** (most common): TDP-43 inclusions; often associated with ALS (e.g., C9orf72 mutations). 2. **FTLD-Tau**: Tau inclusions; includes **Pick disease**, which is characterized by spherical Tau-positive Pick bodies. Note: While Pick bodies are ubiquitinated, TDP-43 is the protein specifically associated with the "ubiquitinated-only" (non-tau) inclusions in FTD.

Flashcard 7: Werdnig-Hoffmann disease is the infantile form (type 1) of _____

Answer: Spinal muscular atrophy (SMA)

Flashcard 8: What lysosomal storage disease presents with central and peripheral demyelination with ataxia and dementia?_____

Answer: Metachromatic leukodystrophy

Flashcard 9: What is the term for infarcted tissue in the basal ganglia or internal capsule caused by occlusion of a lenticulostriate artery?

Answer: lacunar infarct

Flashcard 10: epidural hematoma

Answer: rupture of middle meningeal artery; fracture of temporal bone

Extra: rapid arterial bleedinglucid interval followed by decreased LOC; CN 3 palsy, increased ICPCT: biconvex, hyperdense blood; does not cross sutures; may cross falx, tentorium

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Amyotrophic lateral sclerosis Flashcards for USMLE

Study 10 flashcards on Amyotrophic lateral sclerosis for USMLE Pathology. These active recall cards cover the key concepts, clinical associations, and high-yield facts from this chapter of Neuropathology. Each card is designed to test your understanding rather than just recognition, building stronger and more durable memories for exam day.

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There are 10 flashcards for Amyotrophic lateral sclerosis, covering the key concepts, clinical correlations, and high-yield facts from this chapter of Neuropathology.

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Yes. This page covers one chapter of Neuropathology. Visit the topic page to see all chapters and their flashcards under Pathology.

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