Red blood cell disorders — Flashcards

Flashcard 1: Beta-thalassemia major may be associated with _____ RBCs on blood smear.

Answer: Nucleated RBCs

Flashcard 2: Folate deficiency is characterized by _____ neutrophils

Answer: hypersegmented

Flashcard 3: Does non-megaloblastic macrocytic anemia present with hypersegmented neutrophils? _____

Answer: No

Flashcard 4: What pathologic RBC finding is seen in a peripheral smear with lead and arsenic poisoning, sideroblastic anemia, thalassemia and myelodysplastic syndrome? _____

Answer: Basophilic stippling

Flashcard 5: _____ anemia occurs due to damage of RBCs as they pass through obstructed or narrowed vessels (e.g. due to microthrombi)

Answer: Microangiopathic hemolytic

Flashcard 6: Hereditary spherocytosis is primarily characterized by _____ hemolysis

Answer: extravascular

Flashcard 7: Is polycythemia vera associated with JAK2 mutations?_____

Answer: Yes

Flashcard 8: In G6PD deficiency, Heinz bodies are removed from RBCs by splenic macrophages, resulting in formation of _____ cells

Answer: bite

Flashcard 9: Renal cell carcinoma may present with paraneoplastic syndromes, such as secondary _____ (hematocrit levels)

Answer: polycythemia

Flashcard 10: Most common type of testicular lymphoma?

Answer: Diffuse Large B-cell Lymphoma (DLBCL) is the most common; often represents dissemination from an occult primary site.

Extra: - Most common testicular tumor in men aged >60.\n- Highly aggressive; prognosis is generally poor.\n- Bilateral involvement is common (most common bilateral testicular tumor).