Platelet disorders — Flashcards

Flashcard 1: Glanzmann thrombasthenia presents with _____ bleeding time

Answer: increased

Flashcard 2: TTP and HUS present with _____ platelet count

Answer: decreased

Flashcard 3: Mutations in which proto-oncogene can lead to Chronic Myeloproliferative Disorders?_____

Answer: JAK2

Flashcard 4: In Bernard-Soulier syndrome there is a defect in platelet _____

Answer: adhesion

Flashcard 5: Disorders of fibrinolysis typically present with _____ bleeding time

Answer: increased

Flashcard 6: Is polycythemia vera associated with JAK2 mutations?_____

Answer: Yes

Flashcard 7: In Glanzmann thrombasthenia there is a defect in platelet _____

Answer: aggregation

Flashcard 8: Most common type of testicular lymphoma?

Answer: Diffuse Large B-cell Lymphoma (DLBCL) is the most common; often represents dissemination from an occult primary site.

Extra: - Most common testicular tumor in men aged >60.\n- Highly aggressive; prognosis is generally poor.\n- Bilateral involvement is common (most common bilateral testicular tumor).

Flashcard 9: What kinds of tissue samples can be used for karyotyping?

Answer: blood, bone marrow, amniotic fluid, placental tissue