General Pathology US Medical PG Flashcards - Medical Study Cards
Master General Pathology with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
General Pathology Flashcard Deck - 10 Cards
Flashcard 101: Which immunodeficiency is characterized by impaired phagolysosome formation?
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Answer: Chédiak-Higashi syndrome
Extra:
Watch Phagocytic Cell Disorders [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-immunology/videos/medical-pathophysiology-immunology-immunodeficiency-phagocytic-cell-disorders?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/pediatrics/immunodeficiency/acquire?ref=anki
Flashcard 102: In flow cytometry, cells are tagged with _____ specific to surface or intracellular proteins
Answer: antibodies
Extra:
https://onlinemeded.org?ref=anki
Flashcard 103: _____ can form in the middle ear after hemorrhage and appear as bluish-black gelatinous material behind the tympanic membrane
Answer: Cholesterol granulomas
Extra:
https://onlinemeded.org?ref=anki
Flashcard 104: Which error in morphogenesis is characterized by absent organ due to absent primordial tissue?
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Answer: Agenesis
Extra:
https://onlinemeded.org?ref=anki
Flashcard 105: What type of hypersensitivity reaction is Graves disease and Myasthenia Gravis?
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Answer: Type II HSR (cellular dysfunction)
Extra:
Watch Hyperthyroidism Overview & Graves Disease [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-endocrine/videos/medical-pathophysiology-endocrine-thyroid-and-parathyroid-hyperthyroidism-overview-and-graves-disease?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
Watch Myasthenia Gravis & Lambert Eaton Myasthenic Syndrome [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-endocrine/videos/medical-pathophysiology-endocrine-diabetes-diabetes-mellitus-pathogenesis-and-acute-clinical-manifestations?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/dermatology/hypersensitivity/acquire?ref=anki
Type II hypersensitivity reaction
IgM or IgG recognize and bind to specific antigens on the surface of a cell. This antigen-antibody crosslinking activates the complement cascade resulting in inflammation and a type II hypersensitivity reaction (e.g. acute hemolytic transfusion reaction, autoimmune hemolytic anemia)
- Antigen-bound IgM is a potent complement activator and leads to the generation of membrane attack complex (MAC), a terminal product of the complement cascade. MAC creates holes in the cell membrane and causes cytolysis of the antigen-bearing cell.
- Antigen-bound IgG binds to the Fc receptors (FcR) on the surface of neutrophils and macrophages, inducing cytolysis and phagocytosis respectively. Antigen-bound IgG also activates the complement cascade that generates several activated complement proteins, including C3b that binds to the antigen-bound cell membrane, tagging it to be phagocytosed by macrophages (i.e. opsonization).
IgG is also involved in complement-independent reactions, such as apoptosis, and along with IgM, altering cellular signaling that leads to cell dysfunction and death.
Flashcard 106: Disorders of fibrinolysis are due to _____ overactivity, resulting in excessive cleavage of serum fibrinogen
Answer: plasmin
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/coagulation-and-fibrinolysis?index=5]
https://onlinemeded.org/spa/heme-onc/hemostasis/acquire?ref=anki
Flashcard 107: Wound _____ may occur when there is unusually pronounced MMP activity and myofibroblast accumulation in wound margins
Answer: contractures
Extra:
https://onlinemeded.org/spa/inflammation-and-neoplasia/wound-healing/acquire?ref=anki
Flashcard 108: Is a hexokinase gene mutation associated with maturity-onset diabetes of the young (MODY)?
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Answer: No
Extra:
https://onlinemeded.org/spa/metabolism?ref=anki
Other:
Flashcard 109: Which neurological pathology should be suspected in a patient with bilateral trigeminal neuralgia?
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Answer: Multiple sclerosis
Extra:
* axon becomes completely demyelinated, macrophages disappear, axons and oligodendrocytes are lost
Watch Multiple Sclerosis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-neuro/videos/medical-pathophysiology-neuro-spinal-cord-and-peripheral-nerve-multiple-sclerosis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org?ref=anki
Flashcard 110: Chédiak-Higashi syndrome is associated with defective _____ hemostasis
Answer: primary
Extra:
Watch Phagocytic Cell Disorders [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-immunology/videos/medical-pathophysiology-immunology-immunodeficiency-phagocytic-cell-disorders?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/pediatrics/immunodeficiency/acquire?ref=anki
Keywords: General Pathology flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
