Inflammatory dermatoses — Flashcards

Flashcard 1: Which inflammatory dermatitis has a "saw-tooth" appearance histologically?_____

Answer: Lichen planus

Flashcard 2: _____ is a characterized by well-circumscribed, salmon-colored plaques with silverly scale

Answer: Psoriasis

Flashcard 3: Psoriasis is due to excessive _____ proliferation

Answer: keratinocyte

Flashcard 4: Which blistering skin disorder is characterized by fever and sloughing of skin at the dermal-epidermal junction? _____

Answer: Stevens-Johnson syndrome

Flashcard 5: Which blistering skin disorder is characterized by a targetoid rash and bullae? _____

Answer: Erythema multiforme

Flashcard 6: Which blistering skin disorder is characterized histologically by a "tombstone" appearance? _____

Answer: Pemphigus vulgaris

Flashcard 7: _____ is defined as epidermal accumulation of edematous fluid in intercellular spaces (e.g. eczematous dermatitis)

Answer: Spongiosis

Flashcard 8: Which blistering skin disorder is characterized by acantholysis? _____

Answer: Pemphigus vulgaris

Flashcard 9: What is the underlying defect in albinism?

Answer: Deficiency of tyrosinase enzyme or tyrosine transporters (usually AR)

Extra: Clinical findings: Normal melanocyte count, but decreased melanin production. Very pale or white skin, increased risk for skin cancer (especially SCC). Inheritance is usually Autosomal Recessive.