Dermal tumors and proliferations — Flashcards

Flashcard 1: Which skin cancer typically presents as an elevated nodule with telangiectasias, rolled borders, central crusting, and/or ulcerations? _____

Answer: Basal cell carcinoma (nodular type)

Flashcard 2: _____ is a benign tumor of adipose tissue contained within a fibrous capsule

Answer: Lipoma

Flashcard 3: The tumor cells of a Schwannoma stain positive for _____

Answer: S-100

Flashcard 4: Cutaneous _____ is a malignant tumor associated with chronic lymphedema

Answer: angiosarcoma

Flashcard 5: Which skin cancer presents as a "pink, pearl-like papule"?_____

Answer: Basal cell carcinoma

Flashcard 6: Mutations in which tumor suppressor gene/protein can lead to Neurofibromatosis II?_____

Answer: gene-NFII protein-Merlin (Schwannomin)

Flashcard 7: Cutaneous angiosarcomas are described as firm, _____ nodules

Answer: violaceous (color)

Flashcard 8: What is the underlying defect in albinism?

Answer: Deficiency of tyrosinase enzyme or tyrosine transporters (usually AR)

Extra: Clinical findings: Normal melanocyte count, but decreased melanin production. Very pale or white skin, increased risk for skin cancer (especially SCC). Inheritance is usually Autosomal Recessive.