Prenatal infection screening (TORCH, HIV, STIs) — Flashcards

Flashcard 1: Anencephaly is characterized by _____ levels of AFP in utero

Answer: elevated

Flashcard 2: What are the 4 most common causes of CIN and Cervical Carcinoma?_____

Answer: HPV 16, 18, 31, 33 (high risk HPV)

Flashcard 3: Vaginal and rectal cultures at _____ weeks of pregnancy are done to ensure Group B Streptococcus (GBS) has not colonized.

Answer: 36–37 weeks

Flashcard 4: What types of HPV are the cause of HPV-related vulvar carcinoma?_____

Answer: High Risk HPVs (16, 18, 31, 33)

Flashcard 5: What is the risk of fetal loss in amniocentesis? What about chorionic villus sampling? _____

Answer: 0.5% in amniocentesis versus 1% in CVS

Flashcard 6: What is the most common gynecologic cancer worldwide?_____

Answer: Cervical (due to lack of screening or HPV vaccination)

Flashcard 7: The inability to detect _____ defects is a downside of chorionic villus sampling when compared to amniocentesis

Answer: neural tube

Flashcard 8: Most common high-risk HPV types associated with cervical dysplasia and squamous cell carcinoma?

Answer: HPV 16, 18

Extra: Koilocytes (enlarged, hyperchromatic epithelial cells) on Pap smear. Risk factors: multiple sexual partners, smoking, early age of first intercourse, HIV infection. May progress to invasive carcinoma.

Flashcard 9: Worldwide, _____ cancer is the most common gynecologic tumor.

Answer: cervical

Flashcard 10: secondary prevention (epidemiology)

Answer: early detection (e.g. Pap smear)