Herpesviruses (HSV, VZV, CMV, EBV, HHV-6/7/8) — Flashcards

Flashcard 1: A definitive diagnosis of infectious mononucleosis is made by serologic testing for the EBV _____ antigen

Answer: viral capsid

Flashcard 2: Cytomegalovirus (CMV) is part of the _____ family

Answer: herpesvirus

Flashcard 3: Which virus/viral family will have nuclear, eosinophilic inclusions within cells?

Answer: Herpesvirus family (Cowdry type A bodies)

Flashcard 4: Which herpesvirus is the most common cause of roseola?_____

Answer: HHV-6

Flashcard 5: Which family of viruses does Varicella-Zoster Virus (VZV) belong to?_____

Answer: Herpesvirus family (HHV-3)

Flashcard 6: Which Herpesvirus remains latent in mononuclear cells (monocytes, macrophages)?

Answer: CMV (HHV-5)

Extra: Latency sites of Herpesviruses: - HSV-1, HSV-2, VZV: Sensory ganglia - EBV: B cells - CMV: Mononuclear cells (monocytes, macrophages) - HHV-6, HHV-7: T cells - HHV-8: B cells

Flashcard 7: _____ is the gold standard used in the diagnosis of Herpes Simplex Virus

Answer: PCR

Flashcard 8: Cytomegalovirus (CMV) is a _____ virus

Answer: dsDNA

Flashcard 9: Which immunoglobulin is released into secretions (tears, saliva, mucus)? _____

Answer: IgA

Extra:  Watch associated Bootcamp video [https://app.bootcamp.com/med-school/immunology/videos/antibodies?index=6] https://onlinemeded.org/spa/immunology?ref=anki 

Flashcard 10: Which virus is associated with outbreaks on cruise ships? _____

Answer: Norovirus (norwalk virus)

Extra:  Watch Norovirus/Norwalk virus (Caliciviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-rna-viruses-positive-sense-norovirusnorwalk-virus-caliciviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/infectious-disease?ref=anki