Treponema pallidum US Medical PG Flashcards - Medical Study Cards
Master Treponema pallidum with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Treponema pallidum Flashcard Deck - 10 Cards
Flashcard 1: Which cause of sterile urethritis does not gram stain well?_____
Answer: Chlamydia trachomatis
Flashcard 2: Which stain is used to best visualize Chlamydia?_____
Answer: Giemsa stain
Flashcard 3: What is the vector for Endemic Typhus (Rickettsia typhi)?_____
Answer: Fleas
Flashcard 4: Which stain is best used to visualize Rickettsiae?_____
Answer: Giemsa
Flashcard 5: Name the clinical presentation, culture medium, and treatment for Mycoplasma pneumoniae.
Answer: • Clinical: Atypical "walking" pneumonia
• Culture: Eaton's agar
• Treatment: Macrolides or Fluoroquinolones
Extra: Note: Mycoplasma pneumoniae lacks a cell wall, making it naturally resistant to penicillins and cephalosporins. It is associated with high titers of cold agglutinins (IgM).
Flashcard 6: What are the key associations to remember for cold agglutinin?
Answer: IgM, Mycoplasma, Mononucleosis (EBV)
Flashcard 7: Mycoplasmal pneumonia (Most common cause)
Answer: Which organism is the most common cause of atypical pneumonia (walking pneumonia)?::Mycoplasma pneumoniae (Eaton agent)
Extra: • Features: Insidious onset, headache, nonproductive cough, and diffuse interstitial infiltrates.
• Patient profile: Young adults (<30 y/o), military recruits, and prisoners.
• Diagnosis: PCR, Cold agglutinins (IgM), culture on Eaton agar.
• Treatment: Macrolides (e.g., Azithromycin), Doxycycline, or Fluoroquinolones.
• Note: Lacks a cell wall (does not stain on Gram stain; resistant to β-lactams).
Flashcard 8: What factor explains Mycoplasma's inability to Gram stain?
Answer: no cell wall!
Flashcard 9: What is the Gram stain and morphology of Nocardia spp.?
Answer: Gram-positive branching filaments
Extra: Key features of Nocardia:
- Aerobe
- Weakly acid-fast (modified Ziehl-Neelsen stain)
- Found in soil
- Clinical: Pneumonia/brain abscess in immunocompromised; cutaneous infections after trauma in immunocompetent.
- Treatment: Sulfonamides (e.g., TMP-SMX)
Flashcard 10: tuberculoid leprosy
Answer: Mycobacterium leprae
Extra: few hairless skin plaques6 months of dapsone and rifampin
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