Chlamydia trachomatis US Medical PG Flashcards - Medical Study Cards
Master Chlamydia trachomatis with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Chlamydia trachomatis Flashcard Deck - 10 Cards
Flashcard 1: Which life cycle stage of Chlamydia spp. is extracellular?_____
Answer: Elementary body
Flashcard 2: 1st stage of Chlamydia spp. life cycle: _____
Answer: elementary
Flashcard 3: In the life cycle of _____ spp., reticulate bodies reorganize into elementary bodies before being released by host cell lysis.
Answer: Chlamydia
Flashcard 4: Which life cycle stage of Chlamydia spp. undergoes replication?
Answer: Reticulate Body
Flashcard 5: What stain is used to visualize Chlamydia spp.?_____
Answer: Giemsa
Flashcard 6: Name the clinical presentation, culture medium, and treatment for Mycoplasma pneumoniae.
Answer: • Clinical: Atypical "walking" pneumonia
• Culture: Eaton's agar
• Treatment: Macrolides or Fluoroquinolones
Extra: Note: Mycoplasma pneumoniae lacks a cell wall, making it naturally resistant to penicillins and cephalosporins. It is associated with high titers of cold agglutinins (IgM).
Flashcard 7: What are the key associations to remember for cold agglutinin?
Answer: IgM, Mycoplasma, Mononucleosis (EBV)
Flashcard 8: Mycoplasmal pneumonia (Most common cause)
Answer: Which organism is the most common cause of atypical pneumonia (walking pneumonia)?::Mycoplasma pneumoniae (Eaton agent)
Extra: • Features: Insidious onset, headache, nonproductive cough, and diffuse interstitial infiltrates.
• Patient profile: Young adults (<30 y/o), military recruits, and prisoners.
• Diagnosis: PCR, Cold agglutinins (IgM), culture on Eaton agar.
• Treatment: Macrolides (e.g., Azithromycin), Doxycycline, or Fluoroquinolones.
• Note: Lacks a cell wall (does not stain on Gram stain; resistant to β-lactams).
Flashcard 9: What factor explains Mycoplasma's inability to Gram stain?
Answer: no cell wall!
Flashcard 10: What is the Gram stain and morphology of Nocardia spp.?
Answer: Gram-positive branching filaments
Extra: Key features of Nocardia:
- Aerobe
- Weakly acid-fast (modified Ziehl-Neelsen stain)
- Found in soil
- Clinical: Pneumonia/brain abscess in immunocompromised; cutaneous infections after trauma in immunocompetent.
- Treatment: Sulfonamides (e.g., TMP-SMX)
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