Crystal arthropathies (gout, pseudogout) — Flashcards

Flashcard 1: Gout treatment (NSAIDs, glucocorticoids, colchicine) can also be used to treat _____

Answer: pseudogout

Flashcard 2: Acute gout classically presents as a painful MTP joint of the _____

Answer: big toe (podagra)

Flashcard 3: Acute gout may occur with _____ or seafood consumption, which are foods rich in purines

Answer: red meat

Flashcard 4: What endocrine pathology may be associated with pseudogout?_____

Answer: Hyperparathyroidism

Flashcard 5: Tophi, secondary to gout, often arise on the _____, olecranon bursa, or Achilles tendon

Answer: external ear

Flashcard 6: Patients with Autosomal Dominant Tubulointerstitial Kidney Disease often have early onset _____

Answer: gout

Flashcard 7: Multiple Sclerosis is an autoimmune condition characterized by _____ of the CNS. Classical CSF findings include oligoclonal IgG bands, while MRI typically shows periventricular plaques. Clinical features often include optic neuritis and internuclear ophthalmoplegia.

Answer: demyelination

Extra: - Demyelination of CNS. - Symptoms: Optic neuritis, MLF syndrome (internuclear ophthalmoplegia), hemiparesis, hemisensory loss, bladder/bowel incontinence. - Charcot's Neurologic Triad: Scanning speech, Intention tremor, Nystagmus. - Diagnosis: Oligoclonal IgG bands in CSF, MRI showing periventricular plaques (Dawson fingers). - Treatment: β-interferon, Glatiramer acetate, Natalizumab. Acute flares: IV Steroids.