IBD — Flashcards
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Which immunodeficiency presents with bone fractures from minor trauma? _____
Which form of inflammatory bowel disease typically spares the rectum? _____
What HLA subtype is associated with multiple sclerosis? _____
Patients with a personal or family history chronic _____ diseases are at increased risk for Hodgkin lymphoma/NHL
What drugs may be used to treat microscopic polyangiitis? _____
Hint: 2
Seronegative spondyloarthropathies are associated with HLA-_____
Septic arthritis classically presents as a single red, swollen, and painful joint; usually the _____
Mycobacterium _____ is a non-TB disease that causes disseminated infection in the late stages of AIDS
Inflammatory bowel disease is subclassified as _____ or Crohn disease
Ulcerative colitis may be associated with positive serum _____
IBD US Medical PG Flashcards - Medical Study Cards
Master IBD with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
IBD Flashcard Deck - 225 Cards
Flashcard 1: Which immunodeficiency presents with bone fractures from minor trauma? _____
Answer: Job (hyper-IgE) syndrome
Extra: Watch Phagocytic Cell Disorders [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-immunology/videos/medical-pathophysiology-immunology-immunodeficiency-phagocytic-cell-disorders?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/pediatrics/immunodeficiency/acquire?ref=anki
Flashcard 2: Which form of inflammatory bowel disease typically spares the rectum? _____
Answer: Crohn disease
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki Atlas:
Flashcard 3: What HLA subtype is associated with multiple sclerosis? _____
Answer: DR2
Extra: https://onlinemeded.org/spa/immunology?ref=anki
Flashcard 4: Patients with a personal or family history chronic _____ diseases are at increased risk for Hodgkin lymphoma/NHL
Answer: autoimmune
Extra: * Imagine these two wizards are brothers with a family history of Hodgkin Lymphoma Watch Hodgkin Lymphoma [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-lymphoid-and-plasma-cell-disorders-hodgkin-lymphoma?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki
Flashcard 5: What drugs may be used to treat microscopic polyangiitis? _____
Answer: Cyclophosphamide, corticosteroids
Extra: Watch Small Vessel Vasculitides [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-vascular/videos/medical-pathophysiology-vascular-vasculitides-small-vessel-vasculitides?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/surgery-subspecialty/vascular/acquire?ref=anki
Flashcard 6: Seronegative spondyloarthropathies are associated with HLA-_____
Answer: B27
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki Atlas:
Flashcard 7: Septic arthritis classically presents as a single red, swollen, and painful joint; usually the _____
Answer: knee
Extra: https://onlinemeded.org?ref=anki
Flashcard 8: Mycobacterium _____ is a non-TB disease that causes disseminated infection in the late stages of AIDS
Answer: avium complex
Extra: Watch Leprosy drugs [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antimycobacterials-leprosy-drugs?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/microbiology/antimycobacterials/acquire?ref=anki
Flashcard 9: Inflammatory bowel disease is subclassified as _____ or Crohn disease
Answer: ulcerative colitis
Extra: * Crohn disease (left), Ulcerative colitis (right) Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org?ref=anki
Flashcard 10: Ulcerative colitis may be associated with positive serum _____
Answer: p-ANCA
Extra: Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 11: _____ patients are more likely to have disseminated candidiasis (hematogenous)
Answer: Neutropenic
Extra: Watch Candida albicans [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-fungi/videos/medical-microbiology-fungi-opportunistic-fungal-infections-candida-albicans?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 12: Smoking increases risk for _____
Answer: Crohn disease
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org?ref=anki Atlas:
Flashcard 13: Ulcerative colitis is typically characterized by _____ lower quadrant pain
Answer: left
Extra: Watch Colorectal Polyps & Cancer [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-colorectal-polyps-and-cancer?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki Atlas:
Flashcard 14: Chlamydia trachomatis can cause _____, most commonly of the sacroiliac joint
Answer: reactive arthritis (aka Reiter syndrome)
Extra: Watch Chlamydia trachomatis, Chlamydophila pneumoniae & Chlamydophila psittaci [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-bacteria/videos/medical-microbiology-bacteria-gram-indeterminate-bacteria-chlamydia-trachomatis-chlamydophila-pneumoniae-and-chlamydophila-psittaci?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 15: _____ (IBD) is characterized by continuous colonic lesions that always involve the rectum
Answer: Ulcerative colitis
Extra: Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki "steplike" from the rectangle rectum Atlas:
Flashcard 16: Crohn disease is typically characterized by _____ lower quadrant pain
Answer: right
Extra: Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=3] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki Atlas:
Flashcard 17: The seronegative spondyloarthropathies may be remembered with the mnemonic "PAIR" P: _____ A: Ankylosing spondylitis I: Inflammatory bowel disease R: Reactive arthritis
Answer: Psoriatic arthritis
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki Atlas:
Flashcard 18: One complication of Crohn disease is a(n) _____ fistula, which can cause bowel contents to drain to the surface of the skin
Answer: enterocutaneous
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=3] https://onlinemeded.org?ref=anki
Flashcard 19: IgA deficiency may present with increased infections in _____ sites
Answer: mucosal
Extra: Watch B Cell Disorders & DiGeorge Syndrome [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-immunology/videos/medical-pathophysiology-immunology-immunodeficiency-b-cell-disorders-and-digeorge-syndrome?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/pediatrics/immunodeficiency/acquire?ref=anki
Flashcard 20: A patient with abdominal pain and distension, bloody diarrhea, fever and shock in the setting of ulcerative colitis or Clostridioides difficile is most likely presenting with _____
Answer: Toxic megacolon
Extra: Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki
Flashcard 21: Outside of transplant rejection, Mycophenolate mofetil is used to to treat _____ Nephritis
Answer: Lupus
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/immunology/videos/transplant-rejection?index=14] https://onlinemeded.org/spa/immunology?ref=anki
Flashcard 22: Which form of IBD involves only mucosal and submucosal ulcers? _____
Answer: Ulcerative colitis
Extra: Watch Colorectal Polyps & Cancer [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-colorectal-polyps-and-cancer?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki Atlas:
Flashcard 23: What musculoskeletal pathology is significantly more prevalent in patients with rheumatoid arthritis? _____
Answer: Osteopenia/osteoporosis
Extra: Watch Rheumatoid Arthritis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-joint-rheumatoid-arthritis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/rheumatology/rheumatoid-arthritis/acquire?ref=anki
Flashcard 24: _____ causes interstitial pneumonia with a ground-glass appearance on chest xray
Answer: Pneumocystis pneumonia
Extra: Watch Pneumocystis jirovecii [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-fungi/videos/medical-microbiology-fungi-opportunistic-fungal-infections-pneumocystis-jirovecii?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/infectious-disease/pneumonia/acquire?ref=anki
Flashcard 25: Complications of ulcerative colitis include _____, which may perforate, and fulminant colitis
Answer: toxic megacolon
Extra: Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 26: The Herpes rash is said to have a "_____" appearance
Answer: dew drops on a rose petal
Extra: https://onlinemeded.org/spa/microbiology/dna-viruses/acquire?ref=anki
Flashcard 27: Patients with Systemic Juvenile Idiopathic Arthritis often develop _____ in their eye
Answer: uveitis
Extra: https://onlinemeded.org?ref=anki
Flashcard 28: One complication of Crohn disease is a(n) _____ fistula, which can cause UTI and pneumaturia
Answer: enterovesical
Extra: Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=3] https://onlinemeded.org?ref=anki
Flashcard 29: Uveitis is associated with systemic _____ disorders (e.g. sarcoidosis, rheumatoid arthritis, juvenile idiopathic arthritis, HLA-B27 disorders)
Answer: inflammatory
Extra: https://onlinemeded.org/spa/pediatrics/ophthalmology/acquire?ref=anki
Flashcard 30: Osteoporosis is characterized by _____ serum alkaline phosphatase
Answer: normal
Extra: * important distinguishing feature from osteomalacia AND paget disease of bone (increased ALP) Watch Osteoporosis & Paget Disease of Bone [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-bone-osteoporosis-and-paget-disease-of-bone?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki Atlas:
Flashcard 31: Dissemination of blastomycosis commonly occurs in _____ patients
Answer: immunocompromised
Extra: Watch Blastomyces dermatitidis [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-fungi/videos/medical-microbiology-fungi-systemic-mycoses-blastomyces-dermatitidis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 32: Which form of IBD always causes bloody diarrhea? _____
Answer: Ulcerative colitis
Extra: Watch Colorectal Polyps & Cancer [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-colorectal-polyps-and-cancer?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki Atlas:
Flashcard 33: Normally, patients with atlantoaxial instability often develop neurologic deficits _____ in the disease
Answer: late
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gross-anatomy/videos/back?index=4] https://onlinemeded.org?ref=anki
Flashcard 34: Risk factors for rheumatoid arthritis include HLA-_____, smoking, and silica exposure
Answer: DR4
Extra: Watch Rheumatoid Arthritis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-joint-rheumatoid-arthritis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/rheumatology/rheumatoid-arthritis/acquire?ref=anki ATLAS
Flashcard 35: Interferon β protects the _____ Barrier by preventing extravasation of lymphocytes
Answer: Blood Brain
Extra: https://onlinemeded.org/spa/immunology?ref=anki
Flashcard 36: Chronic Blastomycosis may cause _____
Answer: Osteomyelitis
Extra: Watch Blastomyces dermatitidis [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-fungi/videos/medical-microbiology-fungi-systemic-mycoses-blastomyces-dermatitidis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 37: Is pseudogout more common in males or females? _____
Answer: Both genders affected equally
Extra: Watch Gout & Pseudogout [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-joint-gout-and-pseudogout?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki Atlas:
Flashcard 38: What is the treatment for cryptogenic organizing pneumonia (COP)? _____
Answer: Oral corticosteroids
Extra: Watch Idiopathic Pulmonary Fibrosis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-pulmonary/videos/medical-pathophysiology-pulmonary-restrictive-lung-disease-idiopathic-pulmonary-fibrosis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/pulmonary/restrictive-lung-disease/acquire?ref=anki
Flashcard 39: _____ may appear 1-2 weeks after Herpes Simplex Virus infection
Answer: Erythema multiforme
Extra: https://onlinemeded.org/spa/microbiology/dna-viruses/acquire?ref=anki also a/w mycoplasma, drugs (sulfa, PCN, phenytoin)
Flashcard 40: IL-12 deficiency presents with decreased levels of _____
Answer: IFN-γ
Extra: https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 41: On serum analysis, patients with Systemic Juvenile Idiopathic Arthritis will frequently present with: - _____ RBCs - _____ WBCs - _____ platelets
Answer: decreased
Extra: https://onlinemeded.org?ref=anki Pattern of joint involvement and clinical symptoms of juvenile idiopathic arthritis (JIA) with severe extra-articular manifestations Systemic JIA (Still disease): fever (thermometer), lymphadenopathy (green lymph nodes), serositis (serosa of the lungs, abdomen, and heart), splenomegaly and hepatomegaly (enlarged liver and spleen), transient exanthema (rash on arm) Psoriatic JIA: psoriasis (rash on leg) Enthesitis-related JIA: associated with chronic inflammatory bowel disease (inflamed intestine), may progress to ankylosing spondylitis (red lumbar region), enthesitis (red circles) The most common patterns of joint involvement are circled in red. If associated with uveitis, the eyes are shown; bilateral involvement is common in psoriatic JIA, while unilateral flare-ups are common in enthesitis-related JIA.
Flashcard 42: Progressive multifocal leukoencephalopathy presents with _____ lesion(s)
Answer: many
Extra: Watch JC polyomavirus, BK polyomavirus (Polyomaviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-dna-viruses-jc-polyomavirus-bk-polyomavirus-polyomaviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/neurology/videos/demyelinating-disease?index=6] https://onlinemeded.org/spa/microbiology/dna-viruses/acquire?ref=anki
Flashcard 43: Job (hyper-IgE) syndrome is characterized by _____ IFN-γ
Answer: decreased
Extra: Watch Phagocytic Cell Disorders [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-immunology/videos/medical-pathophysiology-immunology-immunodeficiency-phagocytic-cell-disorders?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/pediatrics/immunodeficiency/acquire?ref=anki
Flashcard 44: Sickle cell anemia patients are at an increased risk of Salmonella typhi _____
Answer: osteomyelitis
Extra: https://onlinemeded.org?ref=anki
Flashcard 45: Which form of IBD is associated with perianal disease, phlegmon/abscess formation, and strictures? _____
Answer: Crohn disease
Extra: Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=3] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki Atlas:
Flashcard 46: Is irritable bowel syndrome related to structural abnormalities? _____
Answer: No
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/intestinal-pathology?index=5] https://onlinemeded.org?ref=anki Colonoscopy reveals normal colonic mucosa
Flashcard 47: Which form of IBD may cause bloody or non-bloody diarrhea? _____
Answer: Crohn disease
Extra: Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=3] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki Atlas:
Flashcard 48: Crohn disease (IBD) is associated with the "_____" sign on imaging, secondary to strictures
Answer: string
Extra: Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki Atlas:
Flashcard 49: Complications associated with Crohn disease (IBD) include gallstones and _____ nephrolithiasis
Answer: calcium oxalate
Extra: Watch Calcium Oxalate Stones & Calcium Phosphate Stones [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-renal/videos/medical-pathophysiology-renal-urinary-tract-obstruction-calcium-oxalate-stones-and-calcium-phosphate-stones?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=3] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki Atlas:
Flashcard 50: Extraintestinal manifestations of IBD include _____, such as erythema nodosum and pyoderma gangrenosum
Answer: rash
Extra: Watch Crohns Disease & Ulcerative Colitis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-crohns-disease-and-ulcerative-colitis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 51: Psoriatic arthritis most commonly involves the _____ joints of the hands and feet
Answer: DIP
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki Atlas:
Flashcard 52: Ulcerative colitis is Th_____ mediated
Answer: 2
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org?ref=anki Atlas:
Flashcard 53: Treatment for acute attacks of multiple sclerosis include high-dose _____
Answer: steroids
Extra: Watch Multiple Sclerosis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-neuro/videos/medical-pathophysiology-neuro-spinal-cord-and-peripheral-nerve-multiple-sclerosis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/neurology/videos/demyelinating-disease?index=4] https://onlinemeded.org?ref=anki
Flashcard 54: JC virus presents when CD4+ count is _____ or with immunosuppressants
Answer: < 200
Extra: Watch JC polyomavirus, BK polyomavirus (Polyomaviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-dna-viruses-jc-polyomavirus-bk-polyomavirus-polyomaviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/neurology/videos/demyelinating-disease?index=6] https://onlinemeded.org/spa/microbiology/dna-viruses/acquire?ref=anki
Flashcard 55: Lymphopenia may occur due to _____ destruction (e.g. SLE)
Answer: autoimmune
Extra: https://onlinemeded.org/spa/hematology-oncology/leukemia/acquire?ref=anki
Flashcard 56: Treatment of IgG-mediated hemolytic anemia involves cessation of the offending drug (if applicable) and _____; may also use IVIG for temporary relief
Answer: steroids
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/normocytic-anemia?index=9] https://onlinemeded.org/spa/hematology-oncology/normocytic-anemia/acquire?ref=anki Other:
Flashcard 57: Seronegative spondyloarthropathies may present with inflammatory back pain that _____ with exercise
Answer: improves
Extra: https://onlinemeded.org/spa/rheumatology/approach-to-joint-pain/acquire?ref=anki Atlas:
Flashcard 58: What demographic is associated with ankylosing spondylitis? _____
Answer: Young adult males
Extra: https://onlinemeded.org?ref=anki Atlas:
Flashcard 59: Treatment for acute exacerbation of Crohn disease often involves _____
Answer: corticosteroids
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=3] https://onlinemeded.org?ref=anki
Flashcard 60: Smoking is protective against _____
Answer: ulcerative colitis
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=2] https://onlinemeded.org?ref=anki Atlas:
Flashcard 61: _____ increases the risk for autoimmune disease, malignancy, and infection *bonus: what is the most common malignancy seen?
Answer: Primary immunodeficiency
Extra: Watch B Cell Disorders & DiGeorge Syndrome [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-immunology/videos/medical-pathophysiology-immunology-immunodeficiency-b-cell-disorders-and-digeorge-syndrome?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/pediatrics/immunodeficiency/acquire?ref=anki
Flashcard 62: Which viral manifestation is said to have a "dew drops on a rose" appearance in a dermatomal distribution? _____
Answer: Herpes Zoster (shingles)
Extra: https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 63: Which form of IBD may cause watery diarrhea and weight loss? _____
Answer: Crohn disease
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 64: What treatment of ankylosing spondylitis is most likely to improve mobility? _____
Answer: TNF-α inhibitors
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki
Flashcard 65: What is alopecia areata? _____ What does it look like? _____
Answer: Autoimmune disorder against hair follicles
Extra: https://onlinemeded.org/spa/dermatology/alopecia/acquire?ref=anki
Flashcard 66: Crohn disease (IBD) = strictures cause "_____" sign
Answer: string
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 67: Mild ulcerative colitis, <4 stools/day (occasionally bloody): _____ Moderate UC, >4 stools/day: _____
Answer: 5-ASA derivatives (mesalamine)
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 68: Which form of inflammatory bowel disease is characterized by continuous colonic involvement? _____
Answer: Ulcerative colitis
Extra: https://onlinemeded.org/spa/gastroenterology/gi-bleed/acquire?ref=anki
Flashcard 69: Which inflammatory ocular condition is associated with systemic inflammatory diseases? _____
Answer: Uveitis
Extra: https://onlinemeded.org/spa/surgery-subspecialty/adult-ophtho/acquire?ref=anki
Flashcard 70: Psoriasis imaging? _____
Answer: Symmetric, well-demarcated silvery scales that bleed when picked
Extra: https://onlinemeded.org/spa/dermatology/papulosquamous/acquire?ref=anki
Flashcard 71: Sympathetic ophthalmia may present as unilateral or bilateral granulomatous _____
Answer: anterior uveitis
Extra: https://onlinemeded.org?ref=anki
Flashcard 72: PPD (-) in those with severe _____
Answer: HIV
Extra: https://onlinemeded.org?ref=anki
Flashcard 73: _____ = malabsorption and nutritional depletion
Answer: Crohn disease
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 74: Toxic megacolon is a medical emergency that requires nasogastric decompression, antibiotics, IV fluids +/- IV _____
Answer: steroids
Extra: https://onlinemeded.org/spa/surgery?ref=anki
Flashcard 75: Diagnostic test for inflammatory bowel disease? _____
Answer: Colonoscopy
Extra: https://onlinemeded.org/spa/surgery?ref=anki
Flashcard 76: What is the management for dacryocystitis? _____
Answer: Oral amoxicillin-clavulanate
Extra: https://onlinemeded.org?ref=anki
Flashcard 77: After how many years of UC is surveillance colonoscopy required? _____
Answer: Colonoscopy q1 yr needed at yr 8 from dx
Extra: https://onlinemeded.org/spa/surgery-general/colorectal/acquire?ref=anki
Flashcard 78: Should antiretroviral treatment be deferred until at least 2 weeks after antifungal treatment is started for cryptococcal infection? _____
Answer: Yes
Extra: https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 79: In _____ rhinitis, nasal mucosa appears erythematous in color
Answer: nonallergic
Extra: https://onlinemeded.org?ref=anki
Flashcard 80: Crohn disease (IBD) is characterized by _____ lesions, which can occur anywhere from the mouth to the anus
Answer: skip
Extra: https://onlinemeded.org/spa/gastroenterology/gi-bleed/acquire?ref=anki
Flashcard 81: When are systemic corticosteroids indicated in UC? _____
Answer: Treatment of active flare
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 82: _____ is associated with a seronegative arthritis that is symmetric and bilateral, non-deforming, peripheral (fingers), and migratory
Answer: Inflammatory bowel disesase
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki
Flashcard 83: What IBD complication presents with colonic dilation on X-ray and fever, tachycardia, leukocytosis, and/or anemia? _____
Answer: Toxic megacolon
Extra: https://onlinemeded.org/spa/surgery?ref=anki
Flashcard 84: What IBD complication presents with colonic dilation on X-ray and fever, tachycardia, leukocytosis, and/or anemia? _____
Answer: Toxic megacolon
Extra: https://onlinemeded.org/spa/surgery?ref=anki
Flashcard 85: What lab value is checked during a suspected IBD flare-up? _____
Answer: Fecal calprotectin
Extra: https://onlinemeded.org?ref=anki
Flashcard 86: Ulcerative colitis may be associated with positive serum _____
Answer: p-ANCA
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 87: Is vision affected in conjunctivitis? _____
Answer: No
Extra: https://onlinemeded.org/spa/surgery-subspecialty/adult-ophtho/acquire?ref=anki
Flashcard 88: What is the likely diagnosis in a young female that presents with a triad of polyarthralgia, tenosynovitis, and a vesiculopustular skin rash? _____
Answer: Disseminated gonococcal infection
Extra: https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 89: What is the likely diagnosis? Described as groups of flesh-colored to erythematous papules that coalesce to form an annular plaque on a distal extremity _____
Answer: Granuloma annulare
Extra: https://onlinemeded.org?ref=anki
Flashcard 90: Classical presentation of Crohn's vs. ulcerative colitis? _____
Answer: Crohn's → watery diarrhea and weight loss UC → bloody diarrhea
Extra: https://onlinemeded.org/spa/gastroenterology/gi-bleed/acquire?ref=anki
Flashcard 91: Smoking results in: _____ risk for Crohn disease _____ risk for Ulcerative colitis
Answer: ↑
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 92: Reactive arthritis is characterized by a triad of _____, _____, and _____
Answer: conjunctivitis
Extra: https://onlinemeded.org/spa/rheumatology/approach-to-joint-pain/acquire?ref=anki
Flashcard 93: Ulcerative colitis = _____ Crohn's = _____
Answer: Start 8 yrs after diagnosis and continue with q1y screening
Extra: https://onlinemeded.org/spa/gastroenterology/colon-cancer/acquire?ref=anki
Flashcard 94: Which arthritis is characterized by non-inflammatory synovial fluid (WBC < 2000/mm3)? _____
Answer: Osteoarthritis
Extra: https://onlinemeded.org?ref=anki
Flashcard 95: Ankylosing spondylitis is characterized by a "_____" appearance on X-ray.
Answer: bamboo spine
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki
Flashcard 96: Which sex is more commonly affected by seronegative spondyloarthritis? _____
Answer: Men
Extra: https://onlinemeded.org/spa/rheumatology/approach-to-joint-pain/acquire?ref=anki
Flashcard 97: What is the recommended treatment for a patient with a 4 mm kidney stone (first episode)? _____
Answer: Hydration (> 2 L fluid intake daily)
Extra: https://onlinemeded.org/spa/nephrology/kidney-stones/acquire?ref=anki
Flashcard 98: _____ antibody is specific for rheumatoid arthritis
Answer: Anti-cyclic citrullinated peptide (anti-CCP)
Extra: https://onlinemeded.org?ref=anki
Flashcard 99: In _____ rhinitis, nasal mucosa appears pale/bluish in color
Answer: allergic
Extra: https://onlinemeded.org?ref=anki
Flashcard 100: In Crohn's disease, _____ absorption is often compromised resulting in its binding to free calcium in the lumen of the GI tract
Answer: fatty acid
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 101: Asthma or CF and productive cough and eosinophilia / ↑ IgE levels is suggestive of _____
Answer: Allergic Bronchopulmonary Asperigillosis (ABPA)
Extra: https://onlinemeded.org?ref=anki
Flashcard 102: What is the most characteristic feature of allergic conjunctivitis? _____
Answer: Itching!
Extra: https://onlinemeded.org?ref=anki
Flashcard 103: _____ is a dermatological condition on the lower limb that is characterized by a central necrotic base and purplish irregular borders
Answer: Pyoderma gangrenosum
Extra: https://onlinemeded.org?ref=anki
Flashcard 104: A pt w/ a history of ulcerative colitis presents c/o of joint pain. History reveals a symmetric, bilateral, non-deforming arthritis affecting the fingers and lower back. What is the most likely dx? _____
Answer: Enteropathic Arthritis
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 105: The seronegative spondyloarthropathies may be remembered with the mnemonic "PAIR" P: _____ A: _____ I: _____ R: _____
Answer: Psoriatic arthritis
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki
Flashcard 106: What is the likely diagnosis in a pregnant patient with Crohn's disease, abdominal pain, nausea, bilious vomiting, fever, and leukocytosis? _____
Answer: Small bowel obstruction
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 107: Pale/boggy mucosa of nasal turbinates, polyps, cobblestoning? _____
Answer: Allergic rhinitis
Extra: https://onlinemeded.org?ref=anki
Flashcard 108: P-ANCA = _____
Answer: Ulcerative colitis
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 109: General treatment of seronegative arthropathies (PAIR) include: (1) _____ (2) Local Steroid injections (3) DMARDs (except axial skeleton) (4) TNF-alpha inhibitors
Answer: NSAIDs
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki
Flashcard 110: Young man with vertebral fusion (bamboo spine) causing back pain and anterior uveitis is suggestive of _____
Answer: ankylosing spondylitis
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki
Flashcard 111: Inflammatory arthritis = _____-_____ WBCs
Answer: 2000
Extra: https://onlinemeded.org/spa/rheumatology/approach-to-joint-pain/acquire?ref=anki
Flashcard 112: What is the likely diagnosis? Nail pitting and onycholysis are most closely associated with? _____
Answer: Psoriasis
Extra: https://onlinemeded.org/spa/dermatology/papulosquamous/acquire?ref=anki
Flashcard 113: Dactylitis (inflammation → sausage fingers) Uveitis Enthesitis (inflammation of tendon, e.g. Achilles) Are common features of _____
Answer: seronegative spondyloarthritis
Extra: https://onlinemeded.org/spa/rheumatology/approach-to-joint-pain/acquire?ref=anki
Flashcard 114: "Lead pipe" sign on imaging = _____
Answer: ulcerative colitis
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 115: Aminopenicillins can cause rash if given in the setting of what viral illness? _____
Answer: EBV infectious mononucleosis
Extra: https://onlinemeded.org?ref=anki
Flashcard 116: _____ is associated with a seronegative arthritis that can affect the axial (spine) or peripheral (knee) joints
Answer: Inflammatory bowel disease
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki
Flashcard 117: Dimpled flesh-colored dome papules = _____
Answer: molluscum contagiosum (often with HIV)
Extra: https://onlinemeded.org/spa/obgyn?ref=anki
Flashcard 118: Patients with Crohn disease have increased risk for kidney stones due to increased absorption of _____
Answer: oxalate
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 119: Chronic bloody diarrhea, abdominal pain and extraintestinal symptoms (e.g. uveitis, arthritis) is suggestive of _____
Answer: UC
Extra: https://onlinemeded.org?ref=anki
Flashcard 120: Which IBD has oral ulcers? _____
Answer: Crohn disease
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 121: What type of kidney stone commonly affects patients with Crohn disease or other causes of fat malabsorption? _____
Answer: Calcium oxalate stones
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 122: Which HLA is associated with seronegative spondyloarthropathies? _____
Answer: HLA-B27
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki
Flashcard 123: What is the treatment of enteropathic (IBD-associated) arthritis? _____
Answer: Treat IBD
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki
Flashcard 124: Inflammatory chronic diarrhea presents with the presence of _____ and _____ in the stool
Answer: blood
Extra: https://onlinemeded.org/spa/gastroenterology/chronic-diarrhea/acquire?ref=anki
Flashcard 125: Pruritic, erythematous, scaly plaques with central clearing = _____
Answer: tinea corporis (dermatophytes)
Extra: https://onlinemeded.org/spa/dermatology/superficial-skin-infections/acquire?ref=anki
Flashcard 126: Reading the PPD test involves checking the size of the _____
Answer: induration
Extra: https://onlinemeded.org?ref=anki
Flashcard 127: What is the most common cause of osteomyelitis in the following populatons: General: _____ Penetrating: _____ Sickle cell: _____ Diabetes mellitus: _____
Answer: Staph aureus
Extra: https://onlinemeded.org?ref=anki
Flashcard 128: Below is a patient with _____
Answer: tinea corporis
Extra: https://onlinemeded.org/spa/dermatology/superficial-skin-infections/acquire?ref=anki
Flashcard 129: _____ is a skin condition associated with Crohn's disease that typically progresses over the course of 1 month
Answer: Pyoderma gangrenosum
Extra: https://onlinemeded.org?ref=anki
Flashcard 130: Ankylosing spondylitis = _____ risk of vertebral fracture
Answer: ↑
Extra: https://onlinemeded.org/spa/rheumatology/seronegative-arthritis/acquire?ref=anki
Flashcard 131: When can you treat UC with surgery? _____
Answer: Refractory to medical tx or with long-standing disease (>8 yrs = malignant transformation)
Extra: https://onlinemeded.org/spa/surgery-general/colorectal/acquire?ref=anki
Flashcard 132: Crohn disease is typically characterized by _____ lower quadrant pain/masses
Answer: right
Extra: https://onlinemeded.org/spa/surgery?ref=anki
Flashcard 133: Smoking is a protective factor for which IBD? _____
Answer: Ulcerative colitis
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 134: What IBD or C. Difficile complication presents with colonic dilation with loss of haustration on X-ray and fever, tachycardia, leukocytosis, and/or anemia? _____
Answer: Toxic megacolon
Extra: https://onlinemeded.org/spa/surgery?ref=anki
Flashcard 135: Anti-Saccharomyces cerevisiae antibodies (ASCAs) are found in 60–70% of individuals with _____ and in 10–20% of individuals with _____
Answer: Crohn disease
Extra: https://onlinemeded.org/spa/gastroenterology/ibd/acquire?ref=anki
Flashcard 136: MMRV and influenza (intranasal) is contraindicated in _____ patients
Answer: immunodeficient
Extra: https://onlinemeded.org/spa/pediatrics/vaccinations/acquire?ref=anki
Flashcard 137: Which classes of immunoglobulin are decreased in ataxia-telangiectasia? _____
Answer: IgA, IgG, and IgE
Flashcard 138: Which classes of immunoglobulin are decreased in hyper-IgM syndrome? _____
Answer: IgA, IgG, and IgE
Flashcard 139: Chronic mucocutaneous candidiasis can result from congenital genetic defects in _____ or its receptor
Answer: IL-17
Flashcard 140: Which immune cells secretes IFN-?_____
Answer: NK cells and Th1 cells (2)
Flashcard 141: What joint pathology is associated with skin psoriasis and nail lesions?_____
Answer: Psoriatic arthritis
Flashcard 142: Many patients with ankylosing spondylitis develop peripheral arthritis and _____ (inflammation at tendon insertion into a bone)
Answer: enthesitis
Flashcard 143: Fibromyalgia is associated with a(n) _____ serum CRP and ESR
Answer: normal
Flashcard 144: _____ pupil is also referred to as relative afferent pupillary defect (RAPD)
Answer: Marcus Gunn
Flashcard 145: Reactive arthritis may cause _____ in about 20% of cases, resulting in axial pain in the lower back / buttocks region
Answer: sacroiliitis
Flashcard 146: Uveitis is associated with HLA-_____ disorders
Answer: B27
Flashcard 147: One complication of chronic lymphocytic leukemia is _____, which predisposes to infection
Answer: hypogammaglobulinemia
Flashcard 148: Which form of IBD has increased risk for gallstones (both cholesterol and pigment)? _____
Answer: Crohn disease
Flashcard 149: Does osteoarthritis present with systemic symptoms (e.g. fever, fatigue)? _____
Answer: No
Flashcard 150: Crohn disease is typically characterized by _____ lower quadrant pain (left or right)
Answer: right
Flashcard 151: JC virus presents when CD4+ count is _____ or with immunosuppressants
Answer: < 200
Flashcard 152: One cause of vitamin B12 deficiency is damage to or resection of the _____ (e.g. Crohn disease)
Answer: terminal ileum
Flashcard 153: Extraintestinal manifestations of IBD include oral _____
Answer: ulcerations (aphthous stomatitis)
Flashcard 154: Septic arthritis classically presents as a single red, swollen, and painful joint; usually the _____
Answer: knee
Flashcard 155: Which form of IBD involves only mucosal and submucosal ulcers? _____
Answer: Ulcerative colitis
Flashcard 156: _____ conjunctivitis is the most common type of conjunctivitis
Answer: Viral
Flashcard 157: Inflammatory bowel disease classically presents in young _____ (gender) with recurrent bloody diarrhea and abdominal pain
Answer: women
Flashcard 158: Treatment for acute attacks of multiple sclerosis include high-dose _____
Answer: steroids
Flashcard 159: The _____ form of ITP is typically self-limited, usually resolving within weeks of presentation
Answer: acute
Flashcard 160: _____ are a group of joint disorders that lack rheumatoid factor and involve the axial skeleton
Answer: Seronegative spondyloarthropathies
Flashcard 161: Cachexia is a syndrome of weight loss, muscle atrophy, and fatigue that occurs in _____ diseases
Answer: chronic
Flashcard 162: Treatment for acute exacerbation of Crohn disease often involves _____
Answer: corticosteroids
Flashcard 163: Progressive multifocal leukoencephalopathy is seen in _____ patients due to reactivation of latent JC virus infection
Answer: immunosuppressed (e.g. AIDS, leukemia)
Flashcard 164: What biliary tract disease is associated with ulcerative colitis? _____
Answer: Primary sclerosing cholangitis
Flashcard 165: Focal segmental glomerulosclerosis has a(n) _____ response to corticosteroids
Answer: poor
Flashcard 166: Progressive multifocal leukoencephalopathy is _____ progressive and usually fatal
Answer: rapidly
Flashcard 167: What neurological pathology commonly causes medial longitudinal fasciculus lesions? _____
Answer: Multiple sclerosis
Flashcard 168: Lymphopenia may occur due to _____ destruction (e.g. SLE)
Answer: autoimmune
Flashcard 169: Progressive multifocal leukoencephalopathy presents with _____ brain lesions in white matter
Answer: non-enhancing (enhancing/non-enhancing)
Flashcard 170: The mature, naive T cell expresses a single _____ receptor on its surface
Answer: T-cell
Flashcard 171: What demographic (age, gender) is associated with Sjogren syndrome? _____
Answer: Older woman (40-60 years old)
Flashcard 172: Symptoms of Restless Legs Syndrome typically worsen or only occur during the _____-time
Answer: night
Flashcard 173: Psoriasis is associated with nail _____ and psoriatic arthritis
Answer: pitting
Flashcard 174: Prophylaxis of HSV with acyclovir is important in _____ patients
Answer: immunocompromised
Flashcard 175: _____ is the precipitation of a urinary solute as a stone
Answer: Nephrolithiasis
Flashcard 176: Extraintestinal manifestations of IBD include _____, such as ankylosing spondylitis, sacroiliitis, migratory polyarthritis, and peripheral joints
Answer: arthritis
Flashcard 177: _____ (IBD) is characterized by continuous colonic lesions that always involve the rectum
Answer: Ulcerative colitis
Flashcard 178: Ankylosing spondylitis involves the spine and _____ joints
Answer: sacroiliac
Flashcard 179: Which form of IBD is associated with perianal disease, phlegmon/abscess formation, and strictures? _____
Answer: Crohn disease
Flashcard 180: Which finger/hand joints (3) are affected in rheumatoid arthritis? _____
Answer: PIPs, MCP, and wrist
Flashcard 181: What HLA subtype is associated with seronegative arthropathies? _____
Answer: B27
Flashcard 182: Iron deficiency anemia is characterized by _____ serum iron
Answer: decreased
Flashcard 183: Nasal polyps are usually secondary to repeated bouts of _____
Answer: rhinitis
Flashcard 184: Adult T-cell leukemia/lymphoma may present with _____ due to skin infiltration
Answer: cutaneous lesions (rash)
Flashcard 185: What skin disorder is caused by autoimmune destruction of melanocytes?_____
Answer: Vitiligo
Flashcard 186: Which form of Rubella, adult or congenital, presents with arthritis?_____
Answer: Adult
Flashcard 187: What two HLA subtypes is Graves disease associated with?_____
Answer: HLA-DR3, HLA-B8
Flashcard 188: One clinical feature of Cushing syndrome is _____, which is a result of inhibition of phospholipase A2, IL-2, and histamine
Answer: immune suppression
Flashcard 189: Which protozoal complication can present with encephalitis and ring enhancing lesions on CT scan?_____
Answer: Toxoplasmosis
Flashcard 190: Histoplasmosis can also cause _____, characterized by painful red nodules, typically on the shins
Answer: erythema nodosum
Flashcard 191: Smoking is protective against _____ (IBD)
Answer: ulcerative colitis
Flashcard 192: Can morning stiffness be experienced in patients with osteoarthritis?_____
Answer: Yes
Flashcard 193: _____ is an autoimmune disorder that initially causes a hyperthyroidism that then becomes a hypothyroidism.
Answer: Hashimoto's Thyroiditis
Flashcard 194: Hemorrhagic cystitis can present with fever and _____
Answer: gross hematuria
Flashcard 195: What movement disorder is associated with Iron Deficiency and Chronic Kidney Disease?_____
Answer: Restless Leg Syndrome
Flashcard 196: Glucocorticoid use may cause candidiasis and reactivation of latent infections, such as _____
Answer: tuberculosis
Flashcard 197: Which form of IBD may cause bloody or non-bloody diarrhea? _____
Answer: Crohn disease
Flashcard 198: In Crohns disease, loss of the innate barrier function of the intestinal mucosa allows intestinal microbes to induce an exaggerated response by the _____, resulting in chronic GI inflammation
Answer: adaptive immune system
Flashcard 199: Which form of IBD is associated with fistula formation? _____
Answer: Crohn disease
Flashcard 200: One complication of Crohn disease is _____ fistula, which can cause UTI and pneumaturia
Answer: enterovesical
Flashcard 201: What GI pathology is associated with calcium oxalate kidney stones?_____
Answer: Crohn's disease
Flashcard 202: Which obstructive lung disease may be caused by allergic bronchopulmonary aspergillosis? _____
Answer: Bronchiectasis
Flashcard 203: Crohn disease most commonly involves the _____
Answer: terminal ileum
Flashcard 204: Ulcerative colitis is typically characterized by _____ lower quadrant pain (left or right)
Answer: left
Flashcard 205: Seronegative spondyloarthropathies may present with inflammatory back pain that _____ with exercise
Answer: improves
Flashcard 206: Treatment for psoriasis includes corticosteroids, _____, or immune-modulating thrapy
Answer: PUVA (psoralen + UV-A light)
Flashcard 207: _____ dermatitis is associated with asthma and allergic rhinitis
Answer: Atopic (eczematous)
Flashcard 208: Smoking increases risk for _____ (IBD)
Answer: Crohn disease
Flashcard 209: Which form of IBD always causes bloody diarrhea? _____
Answer: Ulcerative colitis
Flashcard 210: What MRI finding is associated with multiple sclerosis?_____
Answer: Periventricular plaques
Flashcard 211: Which class of immunoglobulin is increased in Job syndrome? _____
Answer: IgE
Flashcard 212: Seronegative spondyloarthropathies are associated with HLA-_____
Answer: B27
Flashcard 213: Extraintestinal manifestations of IBD include _____ inflammation, such as uveitis and episcleritis
Answer: eye
Flashcard 214: Azathioprine/6-MP can be used to treat _____ disease (crohn's, ulcerative colitis)
Answer: inflammatory bowel
Flashcard 215: Complications of ulcerative colitis include _____, which may perforate, and fulminant colitis
Answer: toxic megacolon
Flashcard 216: Crohn disease usually does NOT affect the _____
Answer: rectum (rectal sparing)
Flashcard 217: Complications of both ulcerative colitis and Crohn disease include malabsorption and _____ cancer
Answer: colorectal
Flashcard 218: Which renal tubular acidosis is highly associated with autoimmune diseases?_____
Answer: Distal RTA (type 1)
Flashcard 219: In the treatment of Crohn's Disease, Natalizumab works by preventing adhesion of autoreactive gut homing _____ cells
Answer: Th17
Flashcard 220: One complication of Crohn disease is a _____, which can cause bowel contents to drain to the surface of the skin
Answer: enterocutaneous fistula
Flashcard 221: _____ refers to a decreased number of circulating neutrophils
Answer: Neutropenia
Flashcard 222: Anemia of chronic disease is characterized by _____ serum iron
Answer: decreased
Flashcard 223: _____ (IBD) is associated with primary sclerosing cholangitis
Answer: Ulcerative colitis
Flashcard 224: Extraintestinal manifestations of IBD include _____, such as erythema nodosum and pyoderma gangrenosum
Answer: rash
Flashcard 225: Which arthritis, osteoarthritis or rheumatoid arthritis, improves with rest? _____
Answer: Osteoarthritis
Keywords: IBD flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
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Crohn's disease pathophysiology
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Ulcerative colitis pathophysiology
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Diagnostic approach to IBD
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Extraintestinal manifestations
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Medical management of Crohn's disease
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Medical management of ulcerative colitis
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Biologic therapies for IBD
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Surgical management in IBD
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Nutritional considerations in IBD
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IBD in pregnancy
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Cancer risk and surveillance in IBD
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IBD-related complications
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IBD in special populations
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