Thalassemias — Flashcards

Flashcard 1: Diagnosis of sickle cell anemia is confirmed by hemoglobin _____

Answer: electrophoresis (test)

Flashcard 2: Iron deficiency anemia is characterized by _____ serum iron

Answer: decreased

Flashcard 3: What type of anemia is caused by TTP, HUS, DIC, and HELLP? _____

Answer: Microangiopathic hemolytic anemia

Flashcard 4: One complication of sickle cell anemia is auto-_____

Answer: splenectomy

Flashcard 5: Thalassemia is an inherited mutation that protects carriers against _____ malaria

Answer: Plasmodium falciparum

Flashcard 6: Hemochromatosis is characterized by _____ TIBC

Answer: decreased

Flashcard 7: priapism

Answer: spinal trauma, sickle cell disease, medications

Extra: painful, sustained erection not associated with sexual desire or stimulation

Flashcard 8: What are the common risk factors for hemorrhagic stroke?

Answer: HTN, anticoagulation, neoplasia, recent ischemic stroke

Extra: These are the most common risk factors/causes for intracerebral hemorrhage (hemorrhagic stroke).

Flashcard 9: What are the classic clinical features and inheritance of hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome)?

Answer: Telangiectasia, recurrent epistaxis, skin discolorations, arteriovenous malformations (AVMs) and Autosomal Dominant (AD) inheritance.

Extra: Hereditary Hemorrhagic Telangiectasia (HHT) is characterized by: 1. Epistaxis 2. Telangiectasias (skin, mucous membranes) 3. Visceral AVMs (lung, liver, brain, GI) 4. Family history (Autosomal Dominant)