Megaloblastic anemias — Flashcards

Flashcard 1: Megaloblastic anemia is a cause of _____ (MCV) anemia

Answer: macrocytic

Flashcard 2: Vitamin B12 deficiency is characterized by _____ (MCV) RBCs

Answer: macrocytic

Flashcard 3: What is the most common cause of vitamin B12 deficiency?_____

Answer: Pernicious anemia

Flashcard 4: priapism

Answer: spinal trauma, sickle cell disease, medications

Extra: painful, sustained erection not associated with sexual desire or stimulation

Flashcard 5: What are the common risk factors for hemorrhagic stroke?

Answer: HTN, anticoagulation, neoplasia, recent ischemic stroke

Extra: These are the most common risk factors/causes for intracerebral hemorrhage (hemorrhagic stroke).

Flashcard 6: What are the classic clinical features and inheritance of hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome)?

Answer: Telangiectasia, recurrent epistaxis, skin discolorations, arteriovenous malformations (AVMs) and Autosomal Dominant (AD) inheritance.

Extra: Hereditary Hemorrhagic Telangiectasia (HHT) is characterized by: 1. Epistaxis 2. Telangiectasias (skin, mucous membranes) 3. Visceral AVMs (lung, liver, brain, GI) 4. Family history (Autosomal Dominant)