Pituitary disorders — Flashcards

Flashcard 1: One possible cause of SIADH is _____ lung carcinoma, which provides a source of ectopic ADH

Answer: small cell

Flashcard 2: _____ is the insufficient production of hormones by the anterior pituitary gland

Answer: Hypopituitarism

Flashcard 3: Empty sella syndrome occurs due to atrophy or compression, and ultimately destruction of the _____ gland

Answer: pituitary

Flashcard 4: If a patient with ACTH-dependent Cushing syndrome has adequate cortisol suppression following a high-dose dexamethasone suppression test (8mg), the most likely cause of their syndrome is _____

Answer: Cushing disease

Flashcard 5: Hypopituitarism may be caused by _____ syndrome, which may occur due to trauma or congenital defect of the sella

Answer: empty sella

Flashcard 6: If a patient with ACTH-dependent Cushing syndrome has no cortisol suppression following a high-dose dexamethasone suppression test (8mg), the most likely cause of their syndrome is _____

Answer: ectopic ACTH secretion

Flashcard 7: Acromegaly is characterized by a large _____ with deep furrows and a deep voice

Answer: tongue

Flashcard 8: What is the most common type of functional pituitary adenoma? _____

Answer: Prolactinoma

Flashcard 9: Kallmann syndrome

Answer: defective migration of GnRH cells

Extra: anosmia, lack of secondary sex characteristicsdecreased: GnRH, FSH, LH, testosterone, sperm count

Flashcard 10: Hormone profile in Hypogonadotropic Hypogonadism (LH/FSH and Sex Steroids)

Answer: Decreased LH/FSH and decreased Testosterone/Estrogen

Extra: Hypogonadotropic hypogonadism (secondary hypogonadism) is characterized by low gonadotropins (LH, FSH) which leads to low sex steroid production. Contrast with Hypergonadotropic hypogonadism (primary): High LH/FSH, low sex steroids.