Sensitivity/Specificity — Flashcards

Raising the **cutoff point** of a diagnostic test will _____ **Specificity** and **PPV**.

How do the following values change when **lowering** the cutoff point of a screening test (e.g., moving the cutoff from point B to point A)? Sensitivity: _____ Specificity: _____ PPV: _____ NPV: _____

For an ROC curve, if the area under the curve (AUC) is: 0.5 = _____ test 1.0 = _____ test

Hint: good/bad

If specificity is 100%, then FP is _____

Hint: ##

A high _____ test is useful for confirmation after a positive screening test

Hint: sensitivity/specificity

What type of disease prevention is screening for disease? _____

Positive predictive value varies _____ with pretest probability (prevalence)

In a standard 2x2 table (Disease on top, Test on side), are **Positive Predictive Value (PPV)** and **Negative Predictive Value (NPV)** calculated horizontally or vertically?

High pre-test probability and negative test = _____ NPV

Negative predictive value varies _____ with pretest probability (prevalence)