Phase III
Are Randomization and Concealment the same? _____
Concealment is critical in preventing _____
_____ risk reduction is the proportion of risk reduction attributable to an intervention compared to a control
Randomization is critical in preventing _____
Are Randomization and Concealment the same? _____
Blinding (the cardinal feature of RCTs) is critical in reducing _____
Relative risk reduction is equal to _____
The number needed to treat (NNT) is equal to _____
Principles and design of RCTs
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Randomization methods
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Allocation concealment
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Blinding techniques and levels
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Sample size determination
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Inclusion and exclusion criteria
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Primary vs secondary outcomes
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Interim analyses
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Intention-to-treat analysis
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Per-protocol analysis
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Crossover designs
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Factorial designs
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Cluster randomization
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Pragmatic vs explanatory trials
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