Deficiency syndromes of fat-soluble vitamins — Flashcards

Flashcard 1: Vitamin B12 deficiency is characterized by _____ serum methylmalonic acid

Answer: increased

Flashcard 2: Vitamin D2 is obtained via _____.

Answer: plants

Flashcard 3: Regeneration of 11-cis retinal (from all-trans retinal) requires vitamin _____

Answer: A

Flashcard 4: Vitamin _____ injection is given at birth to prevent hemorrhagic disease of the newborn

Answer: K

Flashcard 5: Osteomalacia/rickets is characterized by _____ serum PTH

Answer: increased

Flashcard 6: Which coagulation factors (4) have decreased activity due to vitamin K deficiency? _____

Answer: 2, 7, 9, 10

Flashcard 7: Vitamin B12 deficiency may occur with _____ insufficiency; due to inability to cleave R-binder from B12

Answer: pancreatic

Flashcard 8: vitamin B2 (riboflavin)

Answer: component of FADH2, cofactor in redox

Extra: angular chelitis

Flashcard 9: vitamin B3 (niacin)

Answer: component of NAD+, NADP+, cofactor in redox

Extra: 

Flashcard 10: What precursors and cofactors are needed to make vitamin B3 (niacin)?

Answer: Precursor: Tryptophan\nCofactors: Vitamin B2 (Riboflavin) and Vitamin B6 (Pyridoxine)

Extra: Synthesis of niacin from tryptophan requires Vitamin B6 (pyridoxine) and Vitamin B2 (riboflavin). A deficiency in these cofactors can lead to secondary niacin deficiency (Pellagra). \n\nNote: 60 mg of tryptophan yields 1 mg of niacin.