Urea cycle — Flashcards

Which metabolic pathways require an obligate activator? 1. _____ 2. Urea cycle

_____ cleaves the amino acid arginine into citrulline and nitric oxide

The amino acid _____ is essential during periods of positive nitrogen balance

In the liver, glutamate may transfer its NH3 to _____, forming aspartate and α-ketoglutarate

Argininosuccinate may be broken down into _____ and fumarate via the enzyme argininosuccinase

Most excess nitrogen generated by catabolism of amino acids is excreted as _____, which is made in the liver

What is the mode of inheritance of ornithine transcarbamylase (OTC) deficiency? _____

Which tissue/organ uses NH3 as its major transport form of NH3? _____

Does orotic aciduria present with decreased BUN? _____

In the first step of the urea cycle, CO2 and NH4+ are combined to form _____ via the enzyme carbamoyl phosphate synthetase I (requires 2 ATP)