Molecular Genetics — Flashcards

_____ is chromosomal rearrangment between homologous chromosomes

_____ describes the presence of genetically distinct cell lines in the same individual

What gene is defective in Menkes disease? _____

NF-kB activation pathway: the cascade of NF-kB activation is self limiting, as NF-kB stimulates transcription of more _____

p53 induces apoptosis by activating _____ and _____, which dimerize and form a pore in the outer mitochondrial membrane

Lac Operon: Increased cAMP (low glucose) leads to activation of _____, which resides upstream from the promoter, causing increased transcription

Myotonic dystrophy is due to abnormal expression of the enzyme _____

Major histocompatibility complexes (MHCs) are encoded by _____ genes

Down syndrome presents with _____ free β-hCG

Hereditary pancreatitis may be caused by mutations in the cleavage site of trypsinogen or the _____ protein