Rheumatology & Haematology — Flashcards

Flashcard 61: What is the initial screening investigation for infectious mononucleosis? _____

Answer: Monospot (heterophil antibody) test

Flashcard 62: Infectious mononucleosis typically has _____ pharyngitis/tonsilitis

Answer: exudative

Flashcard 63: What is the gold-standard investigation for infectious mononucleosis? _____

Answer: Anti-VCA antibodies (EBV specific)

Flashcard 64: What is the likely diagnosis in a teen with 3-day history of fever, exudative tonsils, posterior cervical lymphadenopathy, & splenomegaly O/E. There is lymphocytosis on FBC and a -ve monospot test. _____

Answer: Infectious mononucleosis

Flashcard 65: Infectious mononucleosis presents with _____itis/tonsilitis, fever, posterior cervical lymphadenopathy, & hepatosplenomegaly

Answer: pharyng

Flashcard 66: What would Bone Marrow Aspirate show in multiple myeloma?

Answer: > 10% plasma cells (clonal)

Extra: Diagnostic criteria for Multiple Myeloma requires clonal bone marrow plasma cells ≥10%. Morphology may show: • 'Fried egg' appearance • Mott cells (multiple cytoplasmic droplets) • Russell bodies (cytoplasmic inclusions) • Flame cells (IgA myeloma)

Flashcard 67: _____ infectious mononucleosis results in +ve Monospot test CMV infectious mononucleosis results in -ve Monospot test

Answer: EBV

Flashcard 68: FBC for infectious mononucleosis shows _____ and >10% atypical lymphocytes

Answer: lymphocytosis

Flashcard 69: Infectious mononucleosis has an incubation period of _____

Answer: ~6 weeks

Flashcard 70: A patient with suspected strep A pharyngitis is treated with amoxicillin develops a maculopapular rash, what is the likely diagnosis? _____

Answer: Infectious mononucleosis