Rheumatology & Haematology — Flashcards

Flashcard 61: When should Sickle Cell patients receive the pneumococcal (PPSV23) booster dose?

Answer: 5 years after the initial dose (one-time booster)

Extra: Patients with functional asplenia (SCD) receive the pneumococcal conjugate vaccine series followed by PPSV23. A single booster of PPSV23 is recommended 5 years after the first PPSV23 dose. Routine revaccination every 5 years thereafter is not currently recommended for most patients.

Flashcard 62: What would Bone Marrow Aspirate show in multiple myeloma?

Answer: > 10% plasma cells (clonal)

Extra: Diagnostic criteria for Multiple Myeloma requires clonal bone marrow plasma cells ≥10%. Morphology may show: • 'Fried egg' appearance • Mott cells (multiple cytoplasmic droplets) • Russell bodies (cytoplasmic inclusions) • Flame cells (IgA myeloma)

Flashcard 63: Infectious mononucleosis has an incubation period of _____

Answer: ~6 weeks

Flashcard 64: FBC for infectious mononucleosis shows _____ and >10% atypical lymphocytes

Answer: lymphocytosis

Flashcard 65: Infectious mononucleosis is transmitted via _____

Answer: saliva

Flashcard 66: Infectious mononucleosis typically has _____ pharyngitis/tonsilitis

Answer: exudative

Flashcard 67: Infectious mononucleosis causes _____megaly that has ↑ risk for rupture

Answer: spleno

Flashcard 68: Infectious mononucleosis presents with _____itis/tonsilitis, fever, posterior cervical lymphadenopathy, & hepatosplenomegaly

Answer: pharyng

Flashcard 69: Pharyngitis/tonsilitis in infectious mononucleosis treated with _____ often results in a(n) maculopapular rash

Answer: aminopenicillins

Flashcard 70: A patient with suspected strep A pharyngitis is treated with amoxicillin develops a maculopapular rash, what is the likely diagnosis? _____

Answer: Infectious mononucleosis