Rheumatology & Haematology — Flashcards

Flashcard 631: What is the management of pernicious anaemia? _____ vitamin B12

Answer: IM

Flashcard 632: Pressure sores present with _____ & non-blanching erythema

Answer: discomfort/tingling

Flashcard 633: Non-Hodgkin's lymphoma is more common in _____

Answer: the elderly (60-70)

Flashcard 634: The spread of Hodgkin's lymphoma is _____ between LN groups

Answer: continuous

Flashcard 635: Lymphoma is staged using the Ann Arbor staging system: Stage 1: _____ Stage 2: ≥2 lymph node regions on the same side of the diaphragm Stage 3: Lymph node regions on both sides of the diaphragm (may include extralymphatic involvement) Stage 4: Diffuse extralymphatic disease A - B symptoms absent B - With B symptoms E - Extra-nodal site involved X - Bulky disease

Answer: Single lymph node region or extralymphatic site

Flashcard 636: Which type of lymphoma has the greatest association with _____? Answer: Burkitt's lymphoma

Answer: EBV

Flashcard 637: _____ of patients diagnosed with NHL survive for >10 years following diagnosis

Answer: 2/3

Flashcard 638: What is the main side effect of _____? Acute pancreatitis

Answer: L-asparaginase

Extra: L-asparaginase depletes serum asparagine, inhibiting protein synthesis. Key side effects: 1. **Acute Pancreatitis** (classic Boards association) 2. **Thrombosis** (due to depletion of Antithrombin III, Protein C, and S) 3. **Hypersensitivity/Anaphylaxis** 4. **Hyperglycemia** (decreased insulin synthesis)

Flashcard 639: There are more than _____ types of Non-Hodgkin's lymphoma which can be broadly categorised into low-grade and high-grade

Answer: 60

Flashcard 640: _____ may be offered for Hodgkin's lymphoma with bulky/resistant disease alongside chemotherapy?

Answer: Radiotherapy