Rheumatology & Haematology — Flashcards

Flashcard 611: Rheumatoid arthritis most commonly affects _____ & feet (which joints?)

Answer: hands

Flashcard 612: Folate deficiency (anaemia) will have _____ Hb ↑ MCV ↑ MCH

Answer: ↓

Flashcard 613: Haemachromatosis is categorised into _____ & secondary (acquired)

Answer: primary (hereditary)

Flashcard 614: Osteoarthritis has a _____ onset

Answer: gradual

Flashcard 615: Rheumatoid arthritis can present with constitutional symptoms: _____, low-grade fever, & weight loss

Answer: fatigue

Flashcard 616: Rheumatoid arthritis is _____ with activity

Answer: improved

Flashcard 617: _____ deficiency = ↑ homocysteine + ↑ methylmalonic acid (MMA) Folate deficiency = ↑ homocysteine + normal/↓ methylmalonic acid (MMA)

Answer: Vitamin B12

Flashcard 618: Vitamin B12 deficiency presents with _____ symptoms ± neurological symptoms

Answer: ANAEMIA

Flashcard 619: On examination patients with vitamin B12 can have _____

Answer: glossitis

Flashcard 620: Patient with suspected folate deficiency is treated with folic acid, but then develops rapidly progressive neurological deficits. What is going on? _____

Answer: Concomitant Vitamin B12 deficiency (folic acid precipitates/worsens neurological damage)

Extra: Always rule out Vitamin B12 deficiency before starting folic acid supplementation in patients with megaloblastic anemia.