Rheumatology & Haematology — Flashcards

Flashcard 551: Why does haemochromatosis affect women at a later age? _____

Answer: Chronic blood loss from menstruation. Usually onsets postmenopausal

Flashcard 552: Rheumatoid arthritis involves a type _____ and type 4 hypersensitivity reaction.

Answer: 3

Extra: While primarily considered a Type III hypersensitivity reaction due to the formation of immune complexes (like Rheumatoid Factor-IgG complexes in the synovium), Type IV hypersensitivity (T-cell mediated) also plays a significant role in the pathogenesis of Rheumatoid Arthritis.

Flashcard 553: Osteoarthritis has morning stiffness for _____

Answer: < 30 minutes

Flashcard 554: Rheumatoid arthritis has morning stiffness for _____

Answer: > 30 minutes

Flashcard 555: Which finger/hand joints are affected in rheumatoid arthritis? _____

Answer: PIPs, MCPs and wrist

Flashcard 556: Herbeden's nodes are bony swellings in _____ joints

Answer: distal interphalangeal (DIP)

Flashcard 557: What is the management for folate deficiency? _____

Answer: Oral folic acid

Flashcard 558: Does folate deficiency present with neurological symptoms? _____

Answer: No, that is vitamin B12 deficiency

Flashcard 559: Hereditary haemochromatosis is _____

Answer: autosommal recessive

Flashcard 560: Primary/hereditary haemochromatosis is a hereditary condition resulting in ↓ _____ (iron regulatory hormone)

Answer: hepcidin