Rheumatology & Haematology — Flashcards

Flashcard 501: What scoring criteria can be used for rheumatoid arthritis severity? _____

Answer: DAS28; often used to monitor treatment efficacy

Flashcard 502: _____ and thiazide diuretics can cause hyperuricemia, which can lead to the precipitation of gout

Answer: Loop

Flashcard 503: _____ has a bimodal distribution at 20 and 60 years.

Answer: Hodgkin Lymphoma

Flashcard 504: In the management of gout, the target serum urate level is < _____ micromol/L (6 mg/dL)

Answer: 360

Extra: Note: Hyperuricemia alone is NOT diagnostic of gout. The gold standard for diagnosis is the presence of negatively birefringent needle-shaped crystals in synovial fluid.

Flashcard 505: Spot diagnosis: Symmetrical arthritis of small joints with _____, swan-neck, and boutonnière deformities = Rheumatoid arthritis

Answer: ulnar deviation

Extra: Classic hand deformities in Rheumatoid Arthritis (RA) include: - Ulnar deviation of the MCP joints. - Swan-neck deformity: Hyperextension of PIP and flexion of DIP. - Boutonnière deformity: Flexion of PIP and hyperextension of DIP.

Flashcard 506: Findings on synovial fluid analysis for gout: _____-shaped -vely birefringent Monosodium urate crystals

Answer: needle

Extra: <b>Gout vs. Pseudogout (CPPD):</b><br>• <b>Gout:</b> Needle-shaped, negatively birefringent, Monosodium urate crystals.<br>• <b>Pseudogout:</b> Rhomboid-shaped, positively birefringent, Calcium pyrophosphate crystals.

Flashcard 507: What is the second-line investigation for gout if serum urate levels are negative? _____

Answer: Joint aspiration & microscopy

Flashcard 508: An obese 35 year old man presents with a severely painful erythematous and swollen first metatarsophalangeal joint over the last 15 hours. What is likely diagnosis? _____

Answer: Gout

Flashcard 509: What is a final management option for rheumatoid arthritis? _____

Answer: Surgical opinion

Flashcard 510: What is the first-line management for fibromyalgia? _____

Answer: Exercise