Rheumatology & Haematology UK Medical PG Flashcards - Medical Study Cards
Master Rheumatology & Haematology with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Rheumatology & Haematology Flashcard Deck - 10 Cards
Flashcard 361: What is the management of anaphylactic transfusion reaction?
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Answer: Stop transfusion, IM adrenaline, ABC support (O2, fluids)
Flashcard 362: What is the likely diagnosis in a patient that develops a fever, chills, flushing, and malaise two hours after starting RBC tranfusion? Coombs test is negative.
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Answer: Febrile non-haemolytic transfusion reaction
Flashcard 363: What is the most common blood transfusion reaction?
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Answer: Febrile non-haemolytic transfusion reaction
Flashcard 364: Which blood transfusion reaction can be caused by ABO incompatability?
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Answer: Acute haemolytic transfusion reaction (AHTR)
Flashcard 365: Delayed transfusion haemolytic transfusion reaction has +ve _____ test
Answer: direct antiglobulin (Coombs)
Flashcard 366: Tranfusions can rarely cause transfusion _____
Answer: reactions
Flashcard 367: What pathologic RBC is associated with myelofibrosis?
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Answer: "Tear drop" cells (dacrocyte)
Flashcard 368: What are the examination finding(s) of myelofibrosis?
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Answer: Massive splenomegaly + hepatomegaly
Flashcard 369: How does myelofibrosis lead to massive splenomegaly (pathophysiology)?
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Answer: Proliferation of megakaryocytes that activate fibroblasts → fibrosis of bone marrow → erythropoiesis is impaired → extramedullary haematopoiesis (esp. spleen & liver) → hepatosplenomegaly
Flashcard 370: What physical exam finding can distinguish myelofibrosis from aplastic anemia?
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Answer: Hepatosplenomegaly
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