Rheumatology & Haematology — Flashcards
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Splenectomy / hyposplenic patients are at risk of _____, which is a bacterial infection that rapidly progresses into overwhelming sepsis
Severe sepsis (gram -ve bacteria), trauma & burns, obstetric complications, malignancy (APL), major surgery are all causes of _____
Hint: haematological condition
_____ is a decrease ↓ in the number of cells in all three major blood cell lines in the peripheral blood leading to ↓ RBC, WBC, & thrombocytes
How do lymphocyte levels change post-splenectomy? _____
Antibiotic prophylaxis in splenectomy/hyposplenic patients who are immunocompromised or had previous post-splenectomy sepsis should be taken for _____ year(s)
Disseminated intravascular coagulation (DIC) may occur secondary to obstetric complications due to activation of the coagulation cascade by _____ in the amniotic fluid
What is the management for a haemodynamically unstable patient with a spleen injury? _____
What vaccinations are used in splenectomy / hyposplenism? _____ Men ACWY (5 yearly), Men B vaccine Hib vaccine (one-off or not needed) Influenza vaccine (anually) to prevent secondary bacterial infections
The RBC abnormalities seen on peripheral blood smear post-splenectomy (or in functional asplenia) include _____.
What is the confirmatory investigation for acute lymphoblastic leukaemia? _____
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