Rheumatology & Haematology — Flashcards

Iron deficiency is caused by 1. dietary _____ 2. increased iron requirement e.g. growth spurt, pregnancy 3. increased iron loss e.g. GI bleeding from malignancy or peptic ulcer disease, menstrual bleeding, frequent blood donation 4. malabsorption e.g. IBD, coeliac disease, bariatric surgery

Sickle cell anaemia has a(n) _____ pattern of inheritance

Iron deficiency anaemia: _____ iron ↓ ferritin ↓ transferrin saturation ↑ total iron-binding capacity (TIBC)

Hint: ↓/↑

Iron deficiency anemia is associated with a(n) _____ red cell distribution width (RDW)

What is the first-line management of iron deficiency anaemia? _____

What lifestyle advice is given to patients with iron deficiency anaemia? _____

What conditions precipiate sickling in sickle cell anaemia? _____ Acidosis Dehydration

What is the most common cause of iron deficiency in females aged 20-50? _____

Hint: 2

_____ is a severe form of hyposplenism where the spleen "self destructs" causing physiological loss of splenic function

_____ is a decrease ↓ in the number of cells in all three major blood cell lines in the peripheral blood leading to ↓ RBC, WBC, & thrombocytes