Rheumatology & Haematology — Flashcards

The most important management in aplastic crisis is _____

Sickle cell disease and fever is managed with _____

Hint: next step

Sickle cell disease can be complicated with _____ from encapsulated organisms causing sepsis, pneumonia, & meningitis

Suspect _____ in patients with sickle cell disease that have chest pain, fever, dyspnoea, & lung infiltrates

Sickle cell disease can cause _____ due to vaso-occlusion in the pulmonary vasculature

One consequence of autosplenectomy in sickle cell disease is increased risk of infection with _____ organisms

What are the major causes of acute severe anaemia in sickle cell disease? _____: ↓ reticulocyte count + no splenomegaly Splenic sequestration (Vaso-occlusion): ↑ reticulocyte count + splenomegaly

Suspect _____ in patients with sickle cell disease that have LUQ tenderness, hypovolaemic shock, & splenomegaly

What RBC pathology is characterised by the following Hb electrophoresis findings: 90% HbS, 8% HbF, and 2% HbA2 (no HbA) _____

Vaso-occlusive crisis is _____ of tissue secondary to microvascular occlusion from sickled RBCs