Endocrinology & Diabetes — Flashcards

_____ should not be added to T2DM treatment until metformin has been titrated up to the final dose

Cushing's disease causes MSK symptoms due to _____ and osteopenia/porosis

Hint: Muscular

Children with Cushing's disease may experience _____ due to suppression of growth hormone secretion or precocious puberty due to increased adrenal androgens

If triple therapy does not control T2DM consider replacement of one drug for a _____

What is the 3rd line management of T2DM if not controlled on dual therapy? _____

Patients who do not tolerate metformin should be switched to _____

Type 2 diabetes target HbA1c levels: Lifestyle alone → _____ Lifestyle + Metformin → 48 mmol/mol Lifestyle + Hypoglycaemia causing drug → 53 mmol/mol Already on 1 drug but HbA1c has risen to 58 mmol/mol → 53 mmol/mol + intensify drug treatment

Patients with suspected Cushing's syndrome who do not experience suppressed cortisol and ACTH following high dose dexamethasone suppression test are likely to have _____

Testicular cancer can present with _____ due to ↑ β-hCG levels

Advanced pancreatic cancer can present with _____ because of loss of endocrine function