Endocrinology & Diabetes — Flashcards

What is the first line management of Cushings DISEASE? 1st Line: _____ 2nd Line: Pituitary radiotherapy OR further surgical removal of the pituitary

_____ should not be added to T2DM treatment until metformin has been titrated up to the final dose

Patients with symptoms of type 2 diabetes can be diagnosed if: • HbA1c is _____ OR • Fasting glucose is ≥7 mmol/L OR • Random glucose/OGTT is ≥11.1 mmol/L

Children with Cushing's disease may experience _____ due to suppression of growth hormone secretion or precocious puberty due to increased adrenal androgens

Cushing's disease causes dermatological symptoms such as _____, acne vulgaris, seborrheic dermatitis

Type 2 diabetes target HbA1c levels: Lifestyle alone → _____ Lifestyle + Metformin → 48 mmol/mol Lifestyle + Hypoglycaemia causing drug → 53 mmol/mol Already on 1 drug but HbA1c has risen to 58 mmol/mol → 53 mmol/mol + intensify drug treatment

Pseudo-cushing's can mimic Cushing's syndrome and is usually due to _____ or severe depression

Cushing's disease causes _____ obesity as well as redistribution of adipose tissue causing moon face and buffalo hump

Testicular cancer can present with _____ due to ↑ β-hCG levels

Advanced pancreatic cancer can present with _____ because of loss of endocrine function