Serious & Notifiable Infections — Flashcards

Flashcard 61: Lyme disease is _____ to be transmitted to a foetus during maternal infection

Answer: unlikely

Flashcard 62: A patient presents with bone pain, systemic signs of infection (e.g., fever, leukocytosis) and +ve blood cultures? _____

Answer: Osteomyelitis

Flashcard 63: What initial investigation can be done for malaria? _____

Answer: Rapid Diagnostic Tests (RDTs); however blood smears are gold-standard and the investigation of choice

Flashcard 64: What is the management of persistent lyme disease symptoms (PTLDS) despite 1 full course of antibiotics?\n_____

Answer: No further antibiotics (supportive/symptomatic care)

Extra: Clinical trials have shown that long-term antibiotic therapy provides no sustained benefit for Post-Treatment Lyme Disease Syndrome (PTLDS) and may cause significant harm. Management is focused on symptomatic relief and supportive care.

Flashcard 65: What is the management for P. falciparum malaria? _____

Answer: ACT; artemether with lumefantrine

Flashcard 66: What is the definitive management of osteomyelitis? _____

Answer: Bone debridement (& IV antibiotics)

Flashcard 67: If there is still a strong suspicion of Lyme disease in patients with a -ve antibody ELISA test who have been symptomatic for ≥12 weeks → _____

Answer: Immunoblot test

Flashcard 68: _____ is classically associated with an erythema migrans rash described as a 'bulls-eye' at the site of a tick bite around 1-4 weeks after

Answer: Lyme disease

Flashcard 69: How is Lyme disease diagnosed in patients WITHOUT erythema migrans? _____ followed by an Immunoblot test if positive or equivocal

Answer: ELISA antibody test

Flashcard 70: Following successful treatment of Lyme disease, patients _____ have lifelong immunity

Answer: Will not