Renal Physiology — Flashcards

_____ clearance can be used to calculate effective renal plasma flow (eRPF) because it is both filtered and secreted

_____ is the major anion reabsorbed in the early PCT

Creatinine clearance slightly _____-estimates GFR because creatinine is moderately secreted by renal tubules

Atrial natriuretic peptide causes vaso-_____ of afferent arterioles and, to a lesser extent, vaso-constriction of efferent arterioles

The _____ of the glomerular filtration barrier contains heparan sulfate, which acts as a negative charge barrier

If the filtered load is _____ than the excretion rate, there has been net secretion (reabsorption or secretion)

The _____ DCT is always impermeable to water (permeability)

In the cells of the proximal tubule, the enzyme _____ metabolizes glutamine to glutamate and NH4+

Decreases in _____ (e.g. hemorrhage or decreased Na+) cause a decrease in renal perfusion pressure, which in turn increases secretion of the enzyme renin

In response to increased Na+ delivery (e.g. increased GFR/RPF), the macula densa releases _____, which constricts the afferent arterioles