Renal Physiology — Flashcards

Creatinine clearance slightly _____-estimates GFR because creatinine is moderately secreted by renal tubules

_____ clearance can be used to calculate effective renal plasma flow (eRPF) because it is both filtered and secreted

The _____ of the glomerular filtration barrier contains heparan sulfate, which acts as a negative charge barrier

Juxtamedullary nephrons have _____ glomeruli (size) and thus higher GFR than superficial cortical nephrons

The effects of ECF volume _____ on the Starling forces result in increased fractional reabsorption of isosmotic fluid in the proximal tubule

Atrial natriuretic peptide causes vaso-_____ of afferent arterioles and, to a lesser extent, vaso-constriction of efferent arterioles

In the _____ of ADH, free-water clearance (CH2O) is positive

In the _____ of the nephron, 50% of the filtered urea is reabsorbed by simple diffusion

In the _____, 70% of the filtered urea is reabsorbed via facilitated diffusion (if ADH is present)

In response to increased Na+ delivery (e.g. increased GFR/RPF), the macula densa releases _____, which constricts the afferent arterioles