Pulmonary Surfactants — Flashcards

Flashcard 1: _____ and Nedocromil prevent mast cell degranulation (used for asthma prophylaxis)

Answer: Cromolyn sodium

Flashcard 2: Which drug is used for treating respiratory depression in newborn due to perinatal opioid use?_____

Answer: Naloxone

Flashcard 3: Nicotine causes _____ of the terminal bronchioles of the lungs

Answer: constriction (dilation/constriction)

Flashcard 4: Leukotrienes _____, D4 and E4 increase airway vascular permeability, mucus production, and bronchoconstriction (bronchospasm)

Answer: C4

Flashcard 5: As per GINA guidelines, _____ + low-dose ICS is the preferred reliever in all cases of asthma irrespective of the severity of the disease.

Answer: formoterol

Flashcard 6: What is the management of choice for moderate persistent asthma?

Answer: Low-dose ICS + LABA (plus SABA as needed)

Extra: According to NAEPP and GINA guidelines: - **Step 3 (Moderate Persistent):** Low-dose ICS + LABA. - **Current GINA Preferred (Track 1):** Maintenance and Reliever Therapy (MART/SMART) using low-dose ICS-formoterol.

Flashcard 7: Ipratropium and tiotropium primarily affect the _____ (organ) via inhibition of M3 muscarinic receptors

Answer: lungs

Flashcard 8: Inhaled _____ is approved for use in persistent pulmonary hypertension.

Answer: nitric oxide (NO)

Flashcard 9: Corticosteroids treat asthma by blocking _____ and cellular infiltration

Answer: inflammation

Flashcard 10: Ipratropium is a competitive _____ receptor antagonist that is used to prevent bronchoconstriction in asthmatic and COPD patients

Answer: M3