Renal and Non-renal Excretion — Flashcards

Renal and Non-renal Excretion — Flashcards

Renal and Non-renal Excretion — Flashcards
#1

Examples of drugs eliminated by zero-order elimination include _____, ethanol, and aspirin (high concentrations)

#2

Doxacurium, pancuronium, vecuronium, and pipecuronium are dependent on _____ for excretion

#3

Aminoglycosides are _____ compounds and are excreted usually unchanged in the urine

Hint: polar/non-polar

#4

Nonbenzodiazepine hypnotics have a _____ duration of action due to rapid metabolism by the liver

#5

If a drug has _____ renal clearance than GFR, then drug is secreted in renal tubules.

#6

Rifampicin is eliminated via the _____ route

#7

Dialysis is _____ in removing the drugs if they are sufficiently present in the free form in the plasma*AVOID dialysis?

#8

What formula is used to calculate loading dose? _____

#9

What formula is used to calculate half-life in first-order elimination kinetics? _____

#10

What formula is used to estimate volume of distribution (Vd)? _____

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