Drug Tolerance and Tachyphylaxis — Flashcards

Drug Tolerance and Tachyphylaxis — Flashcards

Drug Tolerance and Tachyphylaxis — Flashcards
#1

Examples of drugs eliminated by zero-order elimination include _____, ethanol, and aspirin (high concentrations)

#2

Which enzyme in the heme synthesis pathway is induced by barbiturates (and related drugs)?_____

#3

Oxcarbazepine _____ cause auto-induction of metabolizing enzymes.

#4

Cabergoline is a _____-acting D2 agonist

#5

The loading dose of a drug is governed primarily by its _____

#6

_____ is a phenomenon that occurs when tolerance to the effects of one drug produces tolerance to another drug

#7

What formula is used to calculate loading dose? _____

#8

What formula is used to calculate half-life in first-order elimination kinetics? _____

#9

What formula is used to estimate volume of distribution (Vd)? _____

#10

What formula is used to calculate maintenance dose? _____

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