Compartment Models — Flashcards

#1

The nomogram used for vancomycin dosing is the _____ nomogram.

#2

Which parameter is used to asses the extent of drug absorption in a plasma concentration vs. time graph?_____

#3

In first-order kinetics, a drug infused at a constant rate takes _____ - 5 half-lives to reach steady state

#4

Phenytoin follows _____-order kinetics at lower concentrations. As the concentration increases, the elimination changes to zero-order kinetics.

#5

Time for peak plasma concentration (Tmax) of a drug indicates the rate of _____ from the administered site.

#6

The loading dose of a drug is governed primarily by its _____

#7

What formula is used to calculate loading dose? _____

#8

What formula is used to calculate half-life in first-order elimination kinetics? _____

#9

What formula is used to estimate volume of distribution (Vd)? _____

#10

What formula is used to calculate maintenance dose? _____

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