Oxcarbazepine _____ cause auto-induction of metabolizing enzymes.
#2
Phenytoin follows _____-order kinetics at lower concentrations. As the concentration increases, the elimination changes to zero-order kinetics.
#3
Nonbenzodiazepine hypnotics have a _____ duration of action due to rapid metabolism by the liver
#4
If a drug has _____ renal clearance than GFR, then drug is secreted in renal tubules.
#5
Which protease inhibitor undergoes metabolism by CYP2C19 instead of CYP3A4?_____
#6
Succinylcholine and mivacurium are metabolized by the enzyme _____
#7
All barbiturates (thiopentone, thiamylal, methohexital) other than _____ are metabolized by liver
#8
What formula is used to calculate loading dose?
_____
#9
What formula is used to calculate half-life in first-order elimination kinetics?
_____
#10
What formula is used to estimate volume of distribution (Vd)?
_____
Biotransformation and Metabolism Pathways Indian Medical PG Flashcards - Medical Study Cards
Master Biotransformation and Metabolism Pathways with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Biotransformation and Metabolism Pathways Flashcard Deck - 10 Cards
Flashcard 1: Oxcarbazepine _____ cause auto-induction of metabolizing enzymes.
Answer: does not (does/does not)
Flashcard 2: Phenytoin follows _____-order kinetics at lower concentrations. As the concentration increases, the elimination changes to zero-order kinetics.
Answer: first
Flashcard 3: Nonbenzodiazepine hypnotics have a _____ duration of action due to rapid metabolism by the liver
Answer: short
Flashcard 4: If a drug has _____ renal clearance than GFR, then drug is secreted in renal tubules.
Answer: more::more/less
Flashcard 5: Which protease inhibitor undergoes metabolism by CYP2C19 instead of CYP3A4?_____
Answer: Nelfinavir
Flashcard 6: Succinylcholine and mivacurium are metabolized by the enzyme _____
Answer: pseudocholinesterase
Flashcard 7: All barbiturates (thiopentone, thiamylal, methohexital) other than _____ are metabolized by liver
Answer: phenobarbitone
Flashcard 8: What formula is used to calculate loading dose?
_____
Answer:
Flashcard 9: What formula is used to calculate half-life in first-order elimination kinetics?
_____
Answer:
Flashcard 10: What formula is used to estimate volume of distribution (Vd)?
_____
Answer:
Keywords: Biotransformation and Metabolism Pathways flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
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