Age-Related Changes in Pharmacodynamics — Flashcards

Flashcard 1: Which anti-depressant is associated with cardiac abnormalities in newborns?_____

Answer: Paroxetine

Flashcard 2: Oral _____ is FDA approved for medical treatment of type 2 diabetes in pediatric population as young as 10 years of age

Answer: Metformin

Flashcard 3: Drug of choice in an elderly with depression and coronary artery disease is -

Answer: Sertraline

Flashcard 4: Compared to other hypnotics, ramelteon has relatively _____ side effects and is safe to use in geriatric patients

Answer: few

Flashcard 5: An infant weighing >2.5kgs should recieve _____ daily dose of Nevirapine post-partum

Answer: 15mg

Flashcard 6: Antihistamines_____ generation H1 receptor antagonists may cause cognitive impairment and delirium, especially in the elderly

Answer: 1st

Flashcard 7: Bedaquiline can be given to patients aged ≥ _____ years

Answer: 5

Extra: According to current WHO and NTEP guidelines: - Bedaquiline: ≥ 5 years (formerly 18) - Delamanid: ≥ 3 years (formerly 6)

Flashcard 8: pentavalent vaccine contains

Answer: DPT hemophilus influenza(HiB) conjugate hepatitis B

Extra: 

Flashcard 9: Rifampicin _____ once a month + Dapsone 50 mg daily + Clofazimine 150 mg once a month and 50 mg on alternate days is used to treat **multibacillary (MB) leprosy** in children 10-14 years

Answer: 450 mg

Flashcard 10: Rifampicin _____ once a month + dapsone 2mg/kg daily + clofazimine 100mg once a month and 50 mg twice weekly is used to treat leprosy in children less than 10 years or <40kg

Answer: 10mg/kg